Rehm M - Search Results

1

Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism.

Vetma V, Guttà C, Peters N, Praetorius C, Hutt M, Seifert O, Meier F, Kontermann R, Kulms D, Rehm M. Vetma V, et al. Among authors: rehm m. Cell Death Differ. 2020 Aug;27(8):2417-2432. doi: 10.1038/s41418-020-0512-5. Epub 2020 Feb 21. Cell Death Differ. 2020. PMID: 32081986 Free PMC article.

2

Dynamics of outer mitochondrial membrane permeabilization during apoptosis.

Rehm M, Huber HJ, Hellwig CT, Anguissola S, Dussmann H, Prehn JH. Rehm M, et al. Cell Death Differ. 2009 Apr;16(4):613-23. doi: 10.1038/cdd.2008.187. Epub 2009 Jan 9. Cell Death Differ. 2009. PMID: 19136937

3

Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation.

Düssmann H, Rehm M, Concannon CG, Anguissola S, Würstle M, Kacmar S, Völler P, Huber HJ, Prehn JH. Düssmann H, et al. Among authors: rehm m. Cell Death Differ. 2010 Feb;17(2):278-90. doi: 10.1038/cdd.2009.123. Epub 2009 Sep 11. Cell Death Differ. 2010. PMID: 19745831

4

Activity of protein kinase CK2 uncouples Bid cleavage from caspase-8 activation.

Hellwig CT, Ludwig-Galezowska AH, Concannon CG, Litchfield DW, Prehn JH, Rehm M. Hellwig CT, et al. Among authors: rehm m. J Cell Sci. 2010 May 1;123(Pt 9):1401-6. doi: 10.1242/jcs.061143. Epub 2010 Mar 31. J Cell Sci. 2010. PMID: 20356928 Free article.

5

XIAP impairs Smac release from the mitochondria during apoptosis.

Flanagan L, Sebastià J, Tuffy LP, Spring A, Lichawska A, Devocelle M, Prehn JH, Rehm M. Flanagan L, et al. Among authors: rehm m. Cell Death Dis. 2010 Jun 3;1(6):e49. doi: 10.1038/cddis.2010.26. Cell Death Dis. 2010. PMID: 21364655 Free PMC article.

6

Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8.

Laussmann MA, Passante E, Düssmann H, Rauen JA, Würstle ML, Delgado ME, Devocelle M, Prehn JH, Rehm M. Laussmann MA, et al. Among authors: rehm m. Cell Death Differ. 2011 Oct;18(10):1584-97. doi: 10.1038/cdd.2011.27. Epub 2011 Apr 1. Cell Death Differ. 2011. PMID: 21455219 Free PMC article.

7

Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach.

Murphy ÁC, Weyhenmeyer B, Schmid J, Kilbride SM, Rehm M, Huber HJ, Senft C, Weissenberger J, Seifert V, Dunst M, Mittelbronn M, Kögel D, Prehn JH, Murphy BM. Murphy ÁC, et al. Among authors: rehm m. Cell Death Dis. 2013 May 16;4(5):e629. doi: 10.1038/cddis.2013.157. Cell Death Dis. 2013. PMID: 23681224 Free PMC article.

8

Systems analysis of apoptosis protein expression allows the case-specific prediction of cell death responsiveness of melanoma cells.

Passante E, Würstle ML, Hellwig CT, Leverkus M, Rehm M. Passante E, et al. Among authors: rehm m. Cell Death Differ. 2013 Nov;20(11):1521-31. doi: 10.1038/cdd.2013.106. Epub 2013 Aug 9. Cell Death Differ. 2013. PMID: 23933815 Free PMC article.

9

From computational modelling of the intrinsic apoptosis pathway to a systems-based analysis of chemotherapy resistance: achievements, perspectives and challenges in systems medicine.

Würstle ML, Zink E, Prehn JH, Rehm M. Würstle ML, et al. Among authors: rehm m. Cell Death Dis. 2014 May 29;5(5):e1258. doi: 10.1038/cddis.2014.36. Cell Death Dis. 2014. PMID: 24874730 Free PMC article. Review.

10

Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant.

Zakaria Z, Tivnan A, Flanagan L, Murray DW, Salvucci M, Stringer BW, Day BW, Boyd AW, Kögel D, Rehm M, O'Brien DF, Byrne AT, Prehn JH. Zakaria Z, et al. Among authors: rehm m. Br J Cancer. 2016 Jan 19;114(2):188-98. doi: 10.1038/bjc.2015.420. Epub 2015 Dec 10. Br J Cancer. 2016. PMID: 26657652 Free PMC article.

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