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A noninvasive urine-based methylation biomarker panel to detect bladder cancer and discriminate cancer grade.
Hermanns T, Savio AJ, Olkhov-Mitsel E, Mari A, Wettstein MS, Saba K, Bhindi B, Kuk C, Poyet C, Wild PJ, Noon A, Bashir S, Juvet T, Rendon RA, Waltregny D, van der Kwast T, Finelli A, Kulkarni GS, Fleshner NE, Lo K, Bapat B, Zlotta AR. Hermanns T, et al. Urol Oncol. 2020 Jun;38(6):603.e1-603.e7. doi: 10.1016/j.urolonc.2020.01.007. Epub 2020 Feb 18. Urol Oncol. 2020. PMID: 32081560
Detection of urothelial bladder cancer cells in voided urine can be improved by a combination of cytology and standardized microsatellite analysis.
Wild PJ, Fuchs T, Stoehr R, Zimmermann D, Frigerio S, Padberg B, Steiner I, Zwarthoff EC, Burger M, Denzinger S, Hofstaedter F, Kristiansen G, Hermanns T, Seifert HH, Provenzano M, Sulser T, Roth V, Buhmann JM, Moch H, Hartmann A. Wild PJ, et al. Among authors: hermanns t. Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1798-806. doi: 10.1158/1055-9965.EPI-09-0099. Epub 2009 May 19. Cancer Epidemiol Biomarkers Prev. 2009. PMID: 19454613 Free article.
Periostin is up-regulated in high grade and high stage prostate cancer.
Tischler V, Fritzsche FR, Wild PJ, Stephan C, Seifert HH, Riener MO, Hermanns T, Mortezavi A, Gerhardt J, Schraml P, Jung K, Moch H, Soltermann A, Kristiansen G. Tischler V, et al. Among authors: hermanns t. BMC Cancer. 2010 Jun 9;10:273. doi: 10.1186/1471-2407-10-273. BMC Cancer. 2010. PMID: 20534149 Free PMC article.
Insulin-like growth factor II mRNA binding protein 3 (IMP3) is overexpressed in prostate cancer and correlates with higher Gleason scores.
Ikenberg K, Fritzsche FR, Zuerrer-Haerdi U, Hofmann I, Hermanns T, Seifert H, Müntener M, Provenzano M, Sulser T, Behnke S, Gerhardt J, Mortezavi A, Wild P, Hofstädter F, Burger M, Moch H, Kristiansen G. Ikenberg K, et al. Among authors: hermanns t. BMC Cancer. 2010 Jun 30;10:341. doi: 10.1186/1471-2407-10-341. BMC Cancer. 2010. PMID: 20591150 Free PMC article.
KPNA2 expression is an independent adverse predictor of biochemical recurrence after radical prostatectomy.
Mortezavi A, Hermanns T, Seifert HH, Baumgartner MK, Provenzano M, Sulser T, Burger M, Montani M, Ikenberg K, Hofstädter F, Hartmann A, Jaggi R, Moch H, Kristiansen G, Wild PJ. Mortezavi A, et al. Among authors: hermanns t. Clin Cancer Res. 2011 Mar 1;17(5):1111-21. doi: 10.1158/1078-0432.CCR-10-0081. Epub 2011 Jan 10. Clin Cancer Res. 2011. PMID: 21220479 Free article.
222 results