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ABCA12 regulates insulin secretion from β-cells.
Ursino GM, Fu Y, Cottle DL, Mukhamedova N, Jones LK, Low H, Tham MS, Gan WJ, Mellett NA, Das PP, Weir JM, Ditiatkovski M, Fynch S, Thorn P, Thomas HE, Meikle PJ, Parkington HC, Smyth IM, Sviridov D. Ursino GM, et al. Among authors: thomas he. EMBO Rep. 2020 Mar 4;21(3):e48692. doi: 10.15252/embr.201948692. Epub 2020 Feb 18. EMBO Rep. 2020. PMID: 32072744 Free PMC article.
The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity.
Wali JA, Rondas D, McKenzie MD, Zhao Y, Elkerbout L, Fynch S, Gurzov EN, Akira S, Mathieu C, Kay TW, Overbergh L, Strasser A, Thomas HE. Wali JA, et al. Among authors: thomas he. Cell Death Dis. 2014 Mar 13;5(3):e1124. doi: 10.1038/cddis.2014.88. Cell Death Dis. 2014. PMID: 24625983 Free PMC article.
249 results