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Variant antigen diversity in Trypanosoma vivax is not driven by recombination.
Silva Pereira S, de Almeida Castilho Neto KJG, Duffy CW, Richards P, Noyes H, Ogugo M, Rogério André M, Bengaly Z, Kemp S, Teixeira MMG, Machado RZ, Jackson AP. Silva Pereira S, et al. Among authors: duffy cw. Nat Commun. 2020 Feb 12;11(1):844. doi: 10.1038/s41467-020-14575-8. Nat Commun. 2020. PMID: 32051413 Free PMC article.
Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface.
Romero-Ramirez A, Casas-Sánchez A, Autheman D, Duffy CW, Brandt C, Clare S, Harcourt K, André MR, de Almeida Castilho Neto KJG, Teixeira MMG, Machado RZ, Coombes J, Flynn RJ, Wright GJ, Jackson AP. Romero-Ramirez A, et al. Among authors: duffy cw. PLoS Negl Trop Dis. 2022 Sep 21;16(9):e0010791. doi: 10.1371/journal.pntd.0010791. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36129968 Free PMC article.
An invariant Trypanosoma vivax vaccine antigen induces protective immunity.
Autheman D, Crosnier C, Clare S, Goulding DA, Brandt C, Harcourt K, Tolley C, Galaway F, Khushu M, Ong H, Romero-Ramirez A, Duffy CW, Jackson AP, Wright GJ. Autheman D, et al. Among authors: duffy cw. Nature. 2021 Jul;595(7865):96-100. doi: 10.1038/s41586-021-03597-x. Epub 2021 May 26. Nature. 2021. PMID: 34040257
Trypanosome genetics: populations, phenotypes and diversity.
Tait A, Morrison LJ, Duffy CW, Cooper A, Turner CM, Macleod A. Tait A, et al. Among authors: duffy cw. Vet Parasitol. 2011 Sep 8;181(1):61-8. doi: 10.1016/j.vetpar.2011.04.024. Epub 2011 Apr 19. Vet Parasitol. 2011. PMID: 21570772
Trypanosoma vivax displays a clonal population structure.
Duffy CW, Morrison LJ, Black A, Pinchbeck GL, Christley RM, Schoenefeld A, Tait A, Turner CM, MacLeod A. Duffy CW, et al. Int J Parasitol. 2009 Nov;39(13):1475-83. doi: 10.1016/j.ijpara.2009.05.012. Epub 2009 Jun 8. Int J Parasitol. 2009. PMID: 19520081
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