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Integrated Assessment of Viral Transcription, Antigen Presentation, and CD8+ T Cell Function Reveals Multiple Limitations of Class I-Selective Histone Deacetylase Inhibitors during HIV-1 Latency Reversal.
Mota TM, McCann CD, Danesh A, Huang SH, Magat DB, Ren Y, Leyre L, Bui TD, Rohwetter TM, Kovacs CM, Benko E, MacLaren L, Wimpelberg A, Cannon CM, Hardy WD, Safrit JT, Jones RB. Mota TM, et al. J Virol. 2020 Apr 16;94(9):e01845-19. doi: 10.1128/JVI.01845-19. Print 2020 Apr 16. J Virol. 2020. PMID: 32051267 Free PMC article.
HLA-C downregulation by HIV-1 adapts to host HLA genotype.
Bachtel ND, Umviligihozo G, Pickering S, Mota TM, Liang H, Del Prete GQ, Chatterjee P, Lee GQ, Thomas R, Brockman MA, Neil S, Carrington M, Bwana B, Bangsberg DR, Martin JN, Kallas EG, Donini CS, Cerqueira NB, O'Doherty UT, Hahn BH, Jones RB, Brumme ZL, Nixon DF, Apps R. Bachtel ND, et al. Among authors: mota tm. PLoS Pathog. 2018 Sep 4;14(9):e1007257. doi: 10.1371/journal.ppat.1007257. eCollection 2018 Sep. PLoS Pathog. 2018. PMID: 30180214 Free PMC article.
Short Communication: Expression of Host Restriction Factors by Memory CD4+ T Cells Differs Between Healthy Donors and HIV-1-Infected Individuals with Effective Antiretroviral Therapy.
Bachtel ND, Beckerle GA, Mota TM, Rougvie MM, Raposo RAS, Jones RB, Nixon DF, Apps R. Bachtel ND, et al. Among authors: mota tm. AIDS Res Hum Retroviruses. 2019 Jan;35(1):108-111. doi: 10.1089/AID.2018.0162. Epub 2018 Oct 16. AIDS Res Hum Retroviruses. 2019. PMID: 30198299 Free PMC article.
Evidence that CD32a does not mark the HIV-1 latent reservoir.
Osuna CE, Lim SY, Kublin JL, Apps R, Chen E, Mota TM, Huang SH, Ren Y, Bachtel ND, Tsibris AM, Ackerman ME, Jones RB, Nixon DF, Whitney JB. Osuna CE, et al. Among authors: mota tm. Nature. 2018 Sep;561(7723):E20-E28. doi: 10.1038/s41586-018-0495-2. Epub 2018 Sep 19. Nature. 2018. PMID: 30232424 Free PMC article. No abstract available.
Have Cells Harboring the HIV Reservoir Been Immunoedited?
Huang SH, McCann CD, Mota TM, Wang C, Lipkin SM, Jones RB. Huang SH, et al. Among authors: mota tm. Front Immunol. 2019 Aug 6;10:1842. doi: 10.3389/fimmu.2019.01842. eCollection 2019. Front Immunol. 2019. PMID: 31447850 Free PMC article.
BCL-2 antagonism sensitizes cytotoxic T cell-resistant HIV reservoirs to elimination ex vivo.
Ren Y, Huang SH, Patel S, Alberto WDC, Magat D, Ahimovic D, Macedo AB, Durga R, Chan D, Zale E, Mota TM, Truong R, Rohwetter T, McCann CD, Kovacs CM, Benko E, Wimpelberg A, Cannon C, Hardy WD, Bosque A, Bollard CM, Jones RB. Ren Y, et al. Among authors: mota tm. J Clin Invest. 2020 May 1;130(5):2542-2559. doi: 10.1172/JCI132374. J Clin Invest. 2020. PMID: 32027622 Free PMC article.
31 results