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Substrate and Stereochemical Control of Peptidoglycan Cross-Linking by Transpeptidation by Escherichia coli PBP1B.
J Am Chem Soc. 2020 Mar 18;142(11):5034-5048. doi: 10.1021/jacs.9b08822. Epub 2020 Mar 2.
J Am Chem Soc. 2020.
PMID: 32048840
Prospects for novel inhibitors of peptidoglycan transglycosylases.
Galley NF, O'Reilly AM, Roper DI.
Galley NF, et al.
Bioorg Chem. 2014 Aug;55(100):16-26. doi: 10.1016/j.bioorg.2014.05.007. Epub 2014 May 21.
Bioorg Chem. 2014.
PMID: 24924926
Free PMC article.
Review.
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In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA).
Sychantha D, Jones CS, Little DJ, Moynihan PJ, Robinson H, Galley NF, Roper DI, Dowson CG, Howell PL, Clarke AJ.
Sychantha D, et al. Among authors: galley nf.
PLoS Pathog. 2017 Oct 27;13(10):e1006667. doi: 10.1371/journal.ppat.1006667. eCollection 2017 Oct.
PLoS Pathog. 2017.
PMID: 29077761
Free PMC article.
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Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA.
Zuegg J, et al. Among authors: galley nf.
Nat Commun. 2015 Jul 21;6:7719. doi: 10.1038/ncomms8719.
Nat Commun. 2015.
PMID: 26194781
Free PMC article.
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Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a.
Paulin S, Jamshad M, Dafforn TR, Garcia-Lara J, Foster SJ, Galley NF, Roper DI, Rosado H, Taylor PW.
Paulin S, et al. Among authors: galley nf.
Nanotechnology. 2014 Jul 18;25(28):285101. doi: 10.1088/0957-4484/25/28/285101. Epub 2014 Jun 27.
Nanotechnology. 2014.
PMID: 24972373
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Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis.
Roig-Zamboni V, Barelier S, Dixon R, Galley NF, Ghanem A, Nguyen QP, Cahuzac H, Salamaga B, Davis PJ, Bourne Y, Mesnage S, Vincent F.
Roig-Zamboni V, et al. Among authors: galley nf.
J Biol Chem. 2022 May;298(5):101915. doi: 10.1016/j.jbc.2022.101915. Epub 2022 Apr 7.
J Biol Chem. 2022.
PMID: 35398351
Free PMC article.
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Clostridioides difficile canonical L,D-transpeptidases catalyze a novel type of peptidoglycan cross-links and are not required for beta-lactam resistance.
Galley NF, Greetham D, Alamán-Zárate MG, Williamson MP, Evans CA, Spittal WD, Buddle JE, Freeman J, Davis GL, Dickman MJ, Wilcox MH, Lovering AL, Fagan RP, Mesnage S.
Galley NF, et al.
J Biol Chem. 2024 Jan;300(1):105529. doi: 10.1016/j.jbc.2023.105529. Epub 2023 Dec 1.
J Biol Chem. 2024.
PMID: 38043796
Free PMC article.
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A moonlighting role for LysM peptidoglycan binding domains underpins Enterococcus faecalis daughter cell separation.
Salamaga B, Turner RD, Elsarmane F, Galley NF, Kulakauskas S, Mesnage S.
Salamaga B, et al. Among authors: galley nf.
Commun Biol. 2023 Apr 18;6(1):428. doi: 10.1038/s42003-023-04808-z.
Commun Biol. 2023.
PMID: 37072531
Free PMC article.
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