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A Fluorescent Teixobactin Analogue.
Morris MA, Malek M, Hashemian MH, Nguyen BT, Manuse S, Lewis K, Nowick JS. Morris MA, et al. Among authors: lewis k. ACS Chem Biol. 2020 May 15;15(5):1222-1231. doi: 10.1021/acschembio.9b00908. Epub 2020 Feb 26. ACS Chem Biol. 2020. PMID: 32045203 Free PMC article.
Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis.
Homma T, Nuxoll A, Gandt AB, Ebner P, Engels I, Schneider T, Götz F, Lewis K, Conlon BP. Homma T, et al. Among authors: lewis k. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6510-6517. doi: 10.1128/AAC.01050-16. Print 2016 Nov. Antimicrob Agents Chemother. 2016. PMID: 27550357 Free PMC article.
Structural studies suggest aggregation as one of the modes of action for teixobactin.
Öster C, Walkowiak GP, Hughes DE, Spoering AL, Peoples AJ, Catherwood AC, Tod JA, Lloyd AJ, Herrmann T, Lewis K, Dowson CG, Lewandowski JR. Öster C, et al. Among authors: lewis k. Chem Sci. 2018 Sep 20;9(47):8850-8859. doi: 10.1039/c8sc03655a. eCollection 2018 Dec 21. Chem Sci. 2018. PMID: 30627403 Free PMC article.
A new antibiotic selectively kills Gram-negative pathogens.
Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, Böhringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O'Rourke A, Nelson KE, Hiller S, Noinaj N, Schäberle TF, D'Onofrio A, Lewis K. Imai Y, et al. Among authors: lewis k. Nature. 2019 Dec;576(7787):459-464. doi: 10.1038/s41586-019-1791-1. Epub 2019 Nov 20. Nature. 2019. PMID: 31747680 Free PMC article.
Author Correction: A new antibiotic selectively kills Gram-negative pathogens.
Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, Böhringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O'Rourke A, Nelson KE, Hiller S, Noinaj N, Schäberle TF, D'Onofrio A, Lewis K. Imai Y, et al. Among authors: lewis k. Nature. 2020 Apr;580(7802):E3. doi: 10.1038/s41586-020-2063-9. Nature. 2020. PMID: 32269338
2,476 results