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Innate inflammation drives NK cell activation to impair Treg activity.
Dean JW, Peters LD, Fuhrman CA, Seay HR, Posgai AL, Stimpson SE, Brusko MA, Perry DJ, Yeh WI, Newby BN, Haller MJ, Muir AB, Atkinson MA, Mathews CE, Brusko TM. Dean JW, et al. Among authors: mathews ce. J Autoimmun. 2020 Mar;108:102417. doi: 10.1016/j.jaut.2020.102417. Epub 2020 Feb 6. J Autoimmun. 2020. PMID: 32035746 Free PMC article.
Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.
Parker MJ, Xue S, Alexander JJ, Wasserfall CH, Campbell-Thompson ML, Battaglia M, Gregori S, Mathews CE, Song S, Troutt M, Eisenbeis S, Williams J, Schatz DA, Haller MJ, Atkinson MA. Parker MJ, et al. Among authors: mathews ce. Diabetes. 2009 Oct;58(10):2277-84. doi: 10.2337/db09-0557. Epub 2009 Jul 23. Diabetes. 2009. PMID: 19628781 Free PMC article.
Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes.
Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Rosenthal SM, Shuster JJ, Zou B, Brusko TM, Hulme MA, Wasserfall CH, Mathews CE, Atkinson MA, Schatz DA. Haller MJ, et al. Among authors: mathews ce. J Clin Invest. 2015 Jan;125(1):448-55. doi: 10.1172/JCI78492. Epub 2014 Dec 15. J Clin Invest. 2015. PMID: 25500887 Free PMC article. Clinical Trial.
Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.
Xue S, Posgai A, Wasserfall C, Myhr C, Campbell-Thompson M, Mathews CE, Brusko T, Rabinovitch A, Savinov A, Battaglia M, Schatz D, Haller M, Atkinson MA. Xue S, et al. Among authors: mathews ce. Diabetes. 2015 Nov;64(11):3873-84. doi: 10.2337/db15-0164. Epub 2015 Jul 16. Diabetes. 2015. PMID: 26185279 Free PMC article.
Mobilization without immune depletion fails to restore immunological tolerance or preserve beta cell function in recent onset type 1 diabetes.
Haller MJ, Atkinson MA, Wasserfall CH, Brusko TM, Mathews CE, Hulme M, Cintron M, Shuster J, McGrail K, Posgai A, Schatz D. Haller MJ, et al. Among authors: mathews ce. Clin Exp Immunol. 2016 Mar;183(3):350-7. doi: 10.1111/cei.12731. Epub 2015 Dec 7. Clin Exp Immunol. 2016. PMID: 26462724 Free PMC article. Clinical Trial.
Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes.
Richardson SJ, Rodriguez-Calvo T, Gerling IC, Mathews CE, Kaddis JS, Russell MA, Zeissler M, Leete P, Krogvold L, Dahl-Jørgensen K, von Herrath M, Pugliese A, Atkinson MA, Morgan NG. Richardson SJ, et al. Among authors: mathews ce. Diabetologia. 2016 Nov;59(11):2448-2458. doi: 10.1007/s00125-016-4067-4. Epub 2016 Aug 9. Diabetologia. 2016. PMID: 27506584 Free PMC article.
150 results