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Small Molecule Drugs Targeting Viral Polymerases.
Palazzotti D, Sguilla M, Manfroni G, Cecchetti V, Astolfi A, Barreca ML. Palazzotti D, et al. Among authors: manfroni g. Pharmaceuticals (Basel). 2024 May 20;17(5):661. doi: 10.3390/ph17050661. Pharmaceuticals (Basel). 2024. PMID: 38794231 Free PMC article. Review.
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.
Acchioni C, Acchioni M, Mancini F, Amendola A, Marsili G, Tirelli V, Gwee CP, Chan KW, Sandini S, Bisbocci M, Mysara M, ElHefnawi M, Sanchez M, Venturi G, Barreca ML, Manfroni G, Bresciani A, Vasudevan SG, Sgarbanti M. Acchioni C, et al. Among authors: manfroni g. Virology. 2023 Jun;583:1-13. doi: 10.1016/j.virol.2023.03.016. Epub 2023 Apr 5. Virology. 2023. PMID: 37060797 Free article.
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains.
Felicetti T, Cedraro N, Astolfi A, Cernicchi G, Mangiaterra G, Vaiasicca S, Massari S, Manfroni G, Barreca ML, Tabarrini O, Biavasco F, Cecchetti V, Vignaroli C, Sabatini S. Felicetti T, et al. Among authors: manfroni g. Eur J Med Chem. 2022 Nov 5;241:114656. doi: 10.1016/j.ejmech.2022.114656. Epub 2022 Aug 6. Eur J Med Chem. 2022. PMID: 35963131
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