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Author response: The human cough reflex has separate, distinct pathways.
Morice AH, Kitt MM, Ford AP, Tershakovec AM, Wu WC, Brindle K, Thompson R, Thackray-Nocera S, Wright C. Morice AH, et al. Among authors: ford ap. Eur Respir J. 2020 Feb 6;55(2):1902312. doi: 10.1183/13993003.02312-2019. Print 2020 Feb. Eur Respir J. 2020. PMID: 32029646 Free article. No abstract available.
Gefapixant in two randomised dose-escalation studies in chronic cough.
Smith JA, Kitt MM, Butera P, Smith SA, Li Y, Xu ZJ, Holt K, Sen S, Sher MR, Ford AP. Smith JA, et al. Among authors: ford ap. Eur Respir J. 2020 Mar 20;55(3):1901615. doi: 10.1183/13993003.01615-2019. Print 2020 Mar. Eur Respir J. 2020. PMID: 31949115 Free article. Clinical Trial.
Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial.
Smith JA, Kitt MM, Morice AH, Birring SS, McGarvey LP, Sher MR, Li YP, Wu WC, Xu ZJ, Muccino DR, Ford AP; Protocol 012 Investigators. Smith JA, et al. Among authors: ford ap. Lancet Respir Med. 2020 Aug;8(8):775-785. doi: 10.1016/S2213-2600(19)30471-0. Epub 2020 Feb 25. Lancet Respir Med. 2020. PMID: 32109425 Clinical Trial.
The discovery and development of gefapixant.
Ford AP, Dillon MP, Kitt MM, Gever JR. Ford AP, et al. Auton Neurosci. 2021 Nov;235:102859. doi: 10.1016/j.autneu.2021.102859. Epub 2021 Jul 31. Auton Neurosci. 2021. PMID: 34403981
P2X3 receptor antagonism reduces the occurrence of apnoeas in newborn rats.
Katayama PL, Abdala AP, Charles I, Pijacka W, Salgado HC, Gever J, Ford AP, Paton JFR. Katayama PL, et al. Among authors: ford ap. Respir Physiol Neurobiol. 2020 Jun;277:103438. doi: 10.1016/j.resp.2020.103438. Epub 2020 Apr 5. Respir Physiol Neurobiol. 2020. PMID: 32259688 Free PMC article.
111 results