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PARP and PARG inhibitors in cancer treatment.
Slade D. Slade D. Genes Dev. 2020 Mar 1;34(5-6):360-394. doi: 10.1101/gad.334516.119. Epub 2020 Feb 6. Genes Dev. 2020. PMID: 32029455 Free PMC article. Review.
A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Kaufmann T, Grishkovskaya I, Polyansky AA, Kostrhon S, Kukolj E, Olek KM, Herbert S, Beltzung E, Mechtler K, Peterbauer T, Gotzmann J, Zhang L, Hartl M, Zagrovic B, Elsayad K, Djinovic-Carugo K, Slade D. Kaufmann T, et al. Among authors: slade d. Nucleic Acids Res. 2017 Sep 19;45(16):9741-9759. doi: 10.1093/nar/gkx604. Nucleic Acids Res. 2017. PMID: 28934471 Free PMC article.
PARP inhibition causes premature loss of cohesion in cancer cells.
Kukolj E, Kaufmann T, Dick AE, Zeillinger R, Gerlich DW, Slade D. Kukolj E, et al. Among authors: slade d. Oncotarget. 2017 Oct 16;8(61):103931-103951. doi: 10.18632/oncotarget.21879. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262611 Free PMC article.
Mitotic functions of poly(ADP-ribose) polymerases.
Slade D. Slade D. Biochem Pharmacol. 2019 Sep;167:33-43. doi: 10.1016/j.bcp.2019.03.028. Epub 2019 Mar 22. Biochem Pharmacol. 2019. PMID: 30910692 Free PMC article. Review.
Tuning drug binding.
Slade D, Eustermann S. Slade D, et al. Science. 2020 Apr 3;368(6486):30-31. doi: 10.1126/science.abb1462. Science. 2020. PMID: 32241937 Free PMC article. No abstract available.
270 results