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BCL-2 antagonism sensitizes cytotoxic T cell-resistant HIV reservoirs to elimination ex vivo.
Ren Y, Huang SH, Patel S, Alberto WDC, Magat D, Ahimovic D, Macedo AB, Durga R, Chan D, Zale E, Mota TM, Truong R, Rohwetter T, McCann CD, Kovacs CM, Benko E, Wimpelberg A, Cannon C, Hardy WD, Bosque A, Bollard CM, Jones RB. Ren Y, et al. Among authors: mccann cd. J Clin Invest. 2020 May 1;130(5):2542-2559. doi: 10.1172/JCI132374. J Clin Invest. 2020. PMID: 32027622 Free PMC article.
Have Cells Harboring the HIV Reservoir Been Immunoedited?
Huang SH, McCann CD, Mota TM, Wang C, Lipkin SM, Jones RB. Huang SH, et al. Among authors: mccann cd. Front Immunol. 2019 Aug 6;10:1842. doi: 10.3389/fimmu.2019.01842. eCollection 2019. Front Immunol. 2019. PMID: 31447850 Free PMC article.
Integrated Assessment of Viral Transcription, Antigen Presentation, and CD8+ T Cell Function Reveals Multiple Limitations of Class I-Selective Histone Deacetylase Inhibitors during HIV-1 Latency Reversal.
Mota TM, McCann CD, Danesh A, Huang SH, Magat DB, Ren Y, Leyre L, Bui TD, Rohwetter TM, Kovacs CM, Benko E, MacLaren L, Wimpelberg A, Cannon CM, Hardy WD, Safrit JT, Jones RB. Mota TM, et al. Among authors: mccann cd. J Virol. 2020 Apr 16;94(9):e01845-19. doi: 10.1128/JVI.01845-19. Print 2020 Apr 16. J Virol. 2020. PMID: 32051267 Free PMC article.
A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies.
McCann CD, van Dorp CH, Danesh A, Ward AR, Dilling TR, Mota TM, Zale E, Stevenson EM, Patel S, Brumme CJ, Dong W, Jones DS, Andresen TL, Walker BD, Brumme ZL, Bollard CM, Perelson AS, Irvine DJ, Jones RB. McCann CD, et al. J Exp Med. 2021 Jul 5;218(7):e20201908. doi: 10.1084/jem.20201908. Epub 2021 May 14. J Exp Med. 2021. PMID: 33988715 Free PMC article.
Outcomes following posttransplant virus-specific T-cell therapy in patients with sickle cell disease.
Kinoshita H, Mandava M, Jensen-Wachspress M, Lang H, Joy E, Tanna J, McCann CD, O'Brien S, Burnett S, Shibli A, Hoq F, Bhatia M, Hanley PJ, Dávila Saldaña B, Mahadeo KM, Bollard CM, Keller MD, Abraham A. Kinoshita H, et al. Among authors: mccann cd. Blood Adv. 2023 May 23;7(10):2105-2116. doi: 10.1182/bloodadvances.2022008219. Blood Adv. 2023. PMID: 36516084 Free PMC article.
Validation of publicly-available software used in analyzing NGS data for HIV-1 drug resistance mutations and transmission networks in a Washington, DC, Cohort.
Jair K, McCann CD, Reed H, Castel AD, Pérez-Losada M, Wilbourn B, Greenberg AE, Jordan JA; DC Cohort Executive Committee. Jair K, et al. Among authors: mccann cd. PLoS One. 2019 Apr 9;14(4):e0214820. doi: 10.1371/journal.pone.0214820. eCollection 2019. PLoS One. 2019. PMID: 30964884 Free PMC article.
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