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Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling.
Bachmann VA, Mayrhofer JE, Ilouz R, Tschaikner P, Raffeiner P, Röck R, Courcelles M, Apelt F, Lu TW, Baillie GS, Thibault P, Aanstad P, Stelzl U, Taylor SS, Stefan E. Bachmann VA, et al. Among authors: stefan e. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7786-91. doi: 10.1073/pnas.1608061113. Epub 2016 Jun 28. Proc Natl Acad Sci U S A. 2016. PMID: 27357676 Free PMC article.
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.
Rinaldi L, Delle Donne R, Catalanotti B, Torres-Quesada O, Enzler F, Moraca F, Nisticò R, Chiuso F, Piccinin S, Bachmann V, Lindner HH, Garbi C, Scorziello A, Russo NA, Synofzik M, Stelzl U, Annunziato L, Stefan E, Feliciello A. Rinaldi L, et al. Among authors: stefan e. Nat Commun. 2019 Jun 12;10(1):2572. doi: 10.1038/s41467-019-10037-y. Nat Commun. 2019. PMID: 31189917 Free PMC article.
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E. Mayrhofer JE, et al. Among authors: stefan e. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229534 Free PMC article.
Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities.
Fleischmann J, Schwaighofer S, De Falco L, Enzler F, Feichtner A, Kugler V, Tschaikner P, Huber RG, Stefan E. Fleischmann J, et al. Among authors: stefan e. PNAS Nexus. 2023 Jun 5;2(6):pgad185. doi: 10.1093/pnasnexus/pgad185. eCollection 2023 Jun. PNAS Nexus. 2023. PMID: 37325027 Free PMC article.
91 results