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Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab.
Bellier J, Nokin MJ, Caprasse M, Tiamiou A, Blomme A, Scheijen JL, Koopmansch B, MacKay GM, Chiavarina B, Costanza B, Rademaker G, Durieux F, Agirman F, Maloujahmoum N, Cusumano PG, Lovinfosse P, Leung HY, Lambert F, Bours V, Schalkwijk CG, Hustinx R, Peulen O, Castronovo V, Bellahcène A. Bellier J, et al. Among authors: chiavarina b. Cell Rep. 2020 Feb 4;30(5):1400-1416.e6. doi: 10.1016/j.celrep.2020.01.012. Cell Rep. 2020. PMID: 32023458 Free article.
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.
Chiavarina B, Nokin MJ, Bellier J, Durieux F, Bletard N, Sherer F, Lovinfosse P, Peulen O, Verset L, Dehon R, Demetter P, Turtoi A, Uchida K, Goldman S, Hustinx R, Delvenne P, Castronovo V, Bellahcène A. Chiavarina B, et al. Int J Mol Sci. 2017 Jan 21;18(1):213. doi: 10.3390/ijms18010213. Int J Mol Sci. 2017. PMID: 28117708 Free PMC article.
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A. Nokin MJ, et al. Among authors: chiavarina b. Elife. 2016 Oct 19;5:e19375. doi: 10.7554/eLife.19375. Elife. 2016. PMID: 27759563 Free PMC article.
Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis.
Chiavarina B, Costanza B, Ronca R, Blomme A, Rezzola S, Chiodelli P, Giguelay A, Belthier G, Doumont G, Van Simaeys G, Lacroix S, Yokobori T, Erkhem-Ochir B, Balaguer P, Cavailles V, Fabbrizio E, Di Valentin E, Gofflot S, Detry O, Jerusalem G, Goldman S, Delvenne P, Bellahcène A, Pannequin J, Castronovo V, Turtoi A. Chiavarina B, et al. Theranostics. 2021 Jan 1;11(4):1626-1640. doi: 10.7150/thno.51507. eCollection 2021. Theranostics. 2021. PMID: 33408771 Free PMC article.
Fibroblast-derived prolargin is a tumor suppressor in hepatocellular carcinoma.
Chiavarina B, Ronca R, Otaka Y, Sutton RB, Rezzola S, Yokobori T, Chiodelli P, Souche R, Pourquier D, Maraver A, Faa G, Khellaf L, Turtoi E, Oyama T, Gofflot S, Bellahcène A, Detry O, Delvenne P, Castronovo V, Nishiyama M, Turtoi A. Chiavarina B, et al. Oncogene. 2022 Mar;41(10):1410-1420. doi: 10.1038/s41388-021-02171-z. Epub 2022 Jan 14. Oncogene. 2022. PMID: 35031773
The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor.
Creusot N, Gassiot M, Alaterre E, Chiavarina B, Grimaldi M, Boulahtouf A, Toporova L, Gerbal-Chaloin S, Daujat-Chavanieu M, Matheux A, Rahmani R, Gongora C, Evrard A, Pourquier P, Balaguer P. Creusot N, et al. Among authors: chiavarina b. Cells. 2020 Jul 8;9(7):1641. doi: 10.3390/cells9071641. Cells. 2020. PMID: 32650447 Free PMC article.
36 results