Sant'Anna CMR - Search Results

1

Design, Synthesis, and Pharmacological Evaluation of First-in-Class Multitarget N-Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors.

Rodrigues DA, Guerra FS, Sagrillo FS, de Sena M Pinheiro P, Alves MA, Thota S, Chaves LS, Sant'Anna CMR, Fernandes PD, Fraga CAM. Rodrigues DA, et al. Among authors: sant anna cmr. ChemMedChem. 2020 Mar 18;15(6):539-551. doi: 10.1002/cmdc.201900716. Epub 2020 Feb 17. ChemMedChem. 2020. PMID: 32022441

2

Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors.

Rodrigues DA, Ferreira-Silva GÀ, Ferreira AC, Fernandes RA, Kwee JK, Sant'Anna CM, Ionta M, Fraga CA. Rodrigues DA, et al. J Med Chem. 2016 Jan 28;59(2):655-70. doi: 10.1021/acs.jmedchem.5b01525. Epub 2016 Jan 13. J Med Chem. 2016. PMID: 26705137

3

Structural insights into IKKbeta inhibition by natural products staurosporine and quercetin.

Avila CM, Romeiro NC, Sant'Anna CM, Barreiro EJ, Fraga CA. Avila CM, et al. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6907-10. doi: 10.1016/j.bmcl.2009.10.076. Epub 2009 Oct 22. Bioorg Med Chem Lett. 2009. PMID: 19896375

4

Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IκB kinase-β.

Avila CM, Lopes AB, Gonçalves AS, da Silva LL, Romeiro NC, Miranda AL, Sant'Anna CM, Barreiro EJ, Fraga CA. Avila CM, et al. Eur J Med Chem. 2011 Apr;46(4):1245-53. doi: 10.1016/j.ejmech.2011.01.045. Epub 2011 Feb 3. Eur J Med Chem. 2011. PMID: 21334796

5

NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma).

Romeiro NC, Sant'Anna CM, Lima LM, Fraga CA, Barreiro EJ. Romeiro NC, et al. Eur J Med Chem. 2008 Sep;43(9):1918-25. doi: 10.1016/j.ejmech.2007.11.031. Epub 2007 Dec 14. Eur J Med Chem. 2008. PMID: 18222570

6

A proposed molecular basis for the selective resveratrol inhibition of the PGHS-1 peroxidase activity.

Kümmerle AE, Sperandio da Silva GM, Sant'Anna CM, Barreiro EJ, Fraga CA. Kümmerle AE, et al. Bioorg Med Chem. 2005 Nov 1;13(21):5981-5. doi: 10.1016/j.bmc.2005.07.028. Bioorg Med Chem. 2005. PMID: 16099662

7

The molecular basis for coxib inhibition of p38alpha MAP kinase.

Sperandio da Silva GM, Lima LM, Fraga CA, Sant'Anna CM, Barreiro EJ. Sperandio da Silva GM, et al. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3506-9. doi: 10.1016/j.bmcl.2005.05.107. Bioorg Med Chem Lett. 2005. PMID: 15990304

8

Development of new CoMFA and CoMSIA 3D-QSAR models for anti-inflammatory phthalimide-containing TNFalpha modulators.

Avila CM, Romeiro NC, da Silva GM, Sant'Anna CM, Barreiro EJ, Fraga CA. Avila CM, et al. Bioorg Med Chem. 2006 Oct 15;14(20):6874-85. doi: 10.1016/j.bmc.2006.06.042. Epub 2006 Jul 14. Bioorg Med Chem. 2006. PMID: 16843662

9

N-acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity.

Alencar AK, Pereira SL, da Silva FE, Mendes LV, Cunha Vdo M, Lima LM, Montagnoli TL, Caruso-Neves C, Ferraz EB, Tesch R, Nascimento JH, Sant'anna CM, Fraga CA, Barreiro EJ, Sudo RT, Zapata-Sudo G. Alencar AK, et al. Int J Cardiol. 2014 May 1;173(2):154-62. doi: 10.1016/j.ijcard.2014.02.022. Epub 2014 Feb 24. Int J Cardiol. 2014. PMID: 24630383

10

LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A_2A Receptor.

Carvalho VF, Ferreira TPT, de Arantes ACS, Noël F, Tesch R, Sant'Anna CMR, Barreiro EJL, Fraga CAM, Rodrigues E Silva PM, Martins MA. Carvalho VF, et al. Front Pharmacol. 2017 Oct 31;8:778. doi: 10.3389/fphar.2017.00778. eCollection 2017. Front Pharmacol. 2017. PMID: 29163164 Free PMC article.

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