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Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Singh JK, Hutt DM, Tait B, Guy NC, Sivils JC, Ortiz NR, Payan AN, Komaragiri SK, Owens JJ, Culbertson D, Blair LJ, Dickey C, Kuo SY, Finley D, Dyson HJ, Cox MB, Chaudhary J, Gestwicki JE, Balch WE. Singh JK, et al. Among authors: tait b. Cell Chem Biol. 2020 Mar 19;27(3):292-305.e6. doi: 10.1016/j.chembiol.2020.01.008. Epub 2020 Feb 3. Cell Chem Biol. 2020. PMID: 32017918 Free PMC article.
Small-molecule proteostasis regulators for protein conformational diseases.
Calamini B, Silva MC, Madoux F, Hutt DM, Khanna S, Chalfant MA, Saldanha SA, Hodder P, Tait BD, Garza D, Balch WE, Morimoto RI. Calamini B, et al. Among authors: tait bd. Nat Chem Biol. 2011 Dec 25;8(2):185-96. doi: 10.1038/nchembio.763. Nat Chem Biol. 2011. PMID: 22198733 Free PMC article.
Use of a High-Throughput Phenotypic Screening Strategy to Identify Amplifiers, a Novel Pharmacological Class of Small Molecules That Exhibit Functional Synergy with Potentiators and Correctors.
Giuliano KA, Wachi S, Drew L, Dukovski D, Green O, Bastos C, Cullen MD, Hauck S, Tait BD, Munoz B, Lee PS, Miller JP. Giuliano KA, et al. Among authors: tait bd. SLAS Discov. 2018 Feb;23(2):111-121. doi: 10.1177/2472555217729790. Epub 2017 Sep 12. SLAS Discov. 2018. PMID: 28898585 Free PMC article.
Haplotyping the human leukocyte antigen system from single chromosomes.
Murphy NM, Burton M, Powell DR, Rossello FJ, Cooper D, Chopra A, Hsieh MJ, Sayer DC, Gordon L, Pertile MD, Tait BD, Irving HR, Pouton CW. Murphy NM, et al. Among authors: tait bd. Sci Rep. 2016 Jul 27;6:30381. doi: 10.1038/srep30381. Sci Rep. 2016. PMID: 27461731 Free PMC article.
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium; Todd JA, Wallace C, Concannon P, Rich SS. Onengut-Gumuscu S, et al. Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9. Nat Genet. 2015. PMID: 25751624 Free PMC article.
231 results