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Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Singh JK, Hutt DM, Tait B, Guy NC, Sivils JC, Ortiz NR, Payan AN, Komaragiri SK, Owens JJ, Culbertson D, Blair LJ, Dickey C, Kuo SY, Finley D, Dyson HJ, Cox MB, Chaudhary J, Gestwicki JE, Balch WE. Singh JK, et al. Among authors: chaudhary j. Cell Chem Biol. 2020 Mar 19;27(3):292-305.e6. doi: 10.1016/j.chembiol.2020.01.008. Epub 2020 Feb 3. Cell Chem Biol. 2020. PMID: 32017918 Free PMC article.
Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52.
Joshi JB, Patel D, Morton DJ, Sharma P, Zou J, Hewa Bostanthirige D, Gorantla Y, Nagappan P, Komaragiri SK, Sivils JC, Xie H, Palaniappan R, Wang G, Cox MB, Chaudhary J. Joshi JB, et al. Among authors: chaudhary j. Mol Oncol. 2017 Apr;11(4):337-357. doi: 10.1002/1878-0261.12028. Epub 2017 Mar 2. Mol Oncol. 2017. PMID: 28252832 Free PMC article.
ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells.
Komaragiri SK, Bostanthirige DH, Morton DJ, Patel D, Joshi J, Upadhyay S, Chaudhary J. Komaragiri SK, et al. Among authors: chaudhary j. Biochem Biophys Res Commun. 2016 Sep 9;478(1):60-66. doi: 10.1016/j.bbrc.2016.07.092. Epub 2016 Jul 25. Biochem Biophys Res Commun. 2016. PMID: 27462022 Free PMC article.
A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Wojnarowicz PM, Lima E Silva R, Ohnaka M, Lee SB, Chin Y, Kulukian A, Chang SH, Desai B, Garcia Escolano M, Shah R, Garcia-Cao M, Xu S, Kadam R, Goldgur Y, Miller MA, Ouerfelli O, Yang G, Arakawa T, Albanese SK, Garland WA, Stoller G, Chaudhary J, Norton L, Soni RK, Philip J, Hendrickson RC, Iavarone A, Dannenberg AJ, Chodera JD, Pavletich N, Lasorella A, Campochiaro PA, Benezra R. Wojnarowicz PM, et al. Among authors: chaudhary j. Cell Rep. 2019 Oct 1;29(1):62-75.e7. doi: 10.1016/j.celrep.2019.08.073. Cell Rep. 2019. PMID: 31577956 Free PMC article.
194 results