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The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.
Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W. Shimizu K, et al. Among authors: watahiki a. Sci Signal. 2017 Jan 3;10(460):eaah4117. doi: 10.1126/scisignal.aah4117. Sci Signal. 2017. PMID: 28049764 Free PMC article.
NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.
Fukushima H, Shimizu K, Watahiki A, Hoshikawa S, Kosho T, Oba D, Sakano S, Arakaki M, Yamada A, Nagashima K, Okabe K, Fukumoto S, Jimi E, Bigas A, Nakayama KI, Nakayama K, Aoki Y, Wei W, Inuzuka H. Fukushima H, et al. Among authors: watahiki a. Mol Cell. 2017 Nov 16;68(4):645-658.e5. doi: 10.1016/j.molcel.2017.10.018. Mol Cell. 2017. PMID: 29149593 Free PMC article.
Distribution of TRPVs, P2X3, and parvalbumin in the human nodose ganglion.
Sato D, Sato T, Urata Y, Okajima T, Kawamura S, Kurita M, Takahashi K, Nanno M, Watahiki A, Kokubun S, Shimizu Y, Kasahara E, Shoji N, Sasano T, Ichikawa H. Sato D, et al. Among authors: watahiki a. Cell Mol Neurobiol. 2014 Aug;34(6):851-8. doi: 10.1007/s10571-014-0062-9. Epub 2014 Apr 24. Cell Mol Neurobiol. 2014. PMID: 24764033
Integrated analysis of the prostate cancer small-nucleolar transcriptome reveals SNORA55 as a driver of prostate cancer progression.
Crea F, Quagliata L, Michael A, Liu HH, Frumento P, Azad AA, Xue H, Pikor L, Watahiki A, Morant R, Eppenberger-Castori S, Wang Y, Parolia A, Lennox KA, Lam WL, Gleave M, Chi KN, Pandha H, Wang Y, Helgason CD. Crea F, et al. Among authors: watahiki a. Mol Oncol. 2016 May;10(5):693-703. doi: 10.1016/j.molonc.2015.12.010. Epub 2015 Dec 22. Mol Oncol. 2016. PMID: 26809501 Free PMC article.
Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease.
Chapuy B, Cheng H, Watahiki A, Ducar MD, Tan Y, Chen L, Roemer MG, Ouyang J, Christie AL, Zhang L, Gusenleitner D, Abo RP, Farinha P, von Bonin F, Thorner AR, Sun HH, Gascoyne RD, Pinkus GS, van Hummelen P, Wulf GG, Aster JC, Weinstock DM, Monti S, Rodig SJ, Wang Y, Shipp MA. Chapuy B, et al. Among authors: watahiki a. Blood. 2016 May 5;127(18):2203-13. doi: 10.1182/blood-2015-09-672352. Epub 2016 Jan 15. Blood. 2016. PMID: 26773040 Free PMC article.
Next generation patient-derived prostate cancer xenograft models.
Lin D, Xue H, Wang Y, Wu R, Watahiki A, Dong X, Cheng H, Wyatt AW, Collins CC, Gout PW, Wang Y. Lin D, et al. Among authors: watahiki a. Asian J Androl. 2014 May-Jun;16(3):407-12. doi: 10.4103/1008-682X.125394. Asian J Androl. 2014. PMID: 24589467 Free PMC article.
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