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Page 1
In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors.
Nass K, Redecke L, Perbandt M, Yefanov O, Klinge M, Koopmann R, Stellato F, Gabdulkhakov A, Schönherr R, Rehders D, Lahey-Rudolph JM, Aquila A, Barty A, Basu S, Doak RB, Duden R, Frank M, Fromme R, Kassemeyer S, Katona G, Kirian R, Liu H, Majoul I, Martin-Garcia JM, Messerschmidt M, Shoeman RL, Weierstall U, Westenhoff S, White TA, Williams GJ, Yoon CH, Zatsepin N, Fromme P, Duszenko M, Chapman HN, Betzel C. Nass K, et al. Among authors: duszenko m. Nat Commun. 2020 Jan 30;11(1):620. doi: 10.1038/s41467-020-14484-w. Nat Commun. 2020. PMID: 32001697 Free PMC article.
In vivo protein crystallization opens new routes in structural biology.
Koopmann R, Cupelli K, Redecke L, Nass K, Deponte DP, White TA, Stellato F, Rehders D, Liang M, Andreasson J, Aquila A, Bajt S, Barthelmess M, Barty A, Bogan MJ, Bostedt C, Boutet S, Bozek JD, Caleman C, Coppola N, Davidsson J, Doak RB, Ekeberg T, Epp SW, Erk B, Fleckenstein H, Foucar L, Graafsma H, Gumprecht L, Hajdu J, Hampton CY, Hartmann A, Hartmann R, Hauser G, Hirsemann H, Holl P, Hunter MS, Kassemeyer S, Kirian RA, Lomb L, Maia FR, Kimmel N, Martin AV, Messerschmidt M, Reich C, Rolles D, Rudek B, Rudenko A, Schlichting I, Schulz J, Seibert MM, Shoeman RL, Sierra RG, Soltau H, Stern S, Strüder L, Timneanu N, Ullrich J, Wang X, Weidenspointner G, Weierstall U, Williams GJ, Wunderer CB, Fromme P, Spence JC, Stehle T, Chapman HN, Betzel C, Duszenko M. Koopmann R, et al. Among authors: duszenko m. Nat Methods. 2012 Jan 29;9(3):259-62. doi: 10.1038/nmeth.1859. Nat Methods. 2012. PMID: 22286384 Free PMC article.
Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
Redecke L, Nass K, DePonte DP, White TA, Rehders D, Barty A, Stellato F, Liang M, Barends TRM, Boutet S, Williams GJ, Messerschmidt M, Seibert MM, Aquila A, Arnlund D, Bajt S, Barth T, Bogan MJ, Caleman C, Chao TC, Doak RB, Fleckenstein H, Frank M, Fromme R, Galli L, Grotjohann I, Hunter MS, Johansson LC, Kassemeyer S, Katona G, Kirian RA, Koopmann R, Kupitz C, Lomb L, Martin AV, Mogk S, Neutze R, Shoeman RL, Steinbrener J, Timneanu N, Wang D, Weierstall U, Zatsepin NA, Spence JCH, Fromme P, Schlichting I, Duszenko M, Betzel C, Chapman HN. Redecke L, et al. Among authors: duszenko m. Science. 2013 Jan 11;339(6116):227-230. doi: 10.1126/science.1229663. Epub 2012 Nov 29. Science. 2013. PMID: 23196907 Free PMC article.
Real-time investigation of dynamic protein crystallization in living cells.
Schönherr R, Klinge M, Rudolph JM, Fita K, Rehders D, Lübber F, Schneegans S, Majoul IV, Duszenko M, Betzel C, Brandariz-Nuñez A, Martinez-Costas J, Duden R, Redecke L. Schönherr R, et al. Among authors: duszenko m. Struct Dyn. 2015 May 22;2(4):041712. doi: 10.1063/1.4921591. eCollection 2015 Jul. Struct Dyn. 2015. PMID: 26798811 Free PMC article.
In vivo protein crystallization in combination with highly brilliant radiation sources offers novel opportunities for the structural analysis of post-translationally modified eukaryotic proteins.
Duszenko M, Redecke L, Mudogo CN, Sommer BP, Mogk S, Oberthuer D, Betzel C. Duszenko M, et al. Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):929-37. doi: 10.1107/S2053230X15011450. Epub 2015 Jul 29. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26249677 Free PMC article. Review.
Electronic damage in S atoms in a native protein crystal induced by an intense X-ray free-electron laser pulse.
Galli L, Son SK, Klinge M, Bajt S, Barty A, Bean R, Betzel C, Beyerlein KR, Caleman C, Doak RB, Duszenko M, Fleckenstein H, Gati C, Hunt B, Kirian RA, Liang M, Nanao MH, Nass K, Oberthür D, Redecke L, Shoeman R, Stellato F, Yoon CH, White TA, Yefanov O, Spence J, Chapman HN. Galli L, et al. Among authors: duszenko m. Struct Dyn. 2015 Apr 29;2(4):041703. doi: 10.1063/1.4919398. eCollection 2015 Jul. Struct Dyn. 2015. PMID: 26798803 Free PMC article.
Serial crystallography on in vivo grown microcrystals using synchrotron radiation.
Gati C, Bourenkov G, Klinge M, Rehders D, Stellato F, Oberthür D, Yefanov O, Sommer BP, Mogk S, Duszenko M, Betzel C, Schneider TR, Chapman HN, Redecke L. Gati C, et al. Among authors: duszenko m. IUCrJ. 2014 Feb 10;1(Pt 2):87-94. doi: 10.1107/S2052252513033939. eCollection 2014 Mar 1. IUCrJ. 2014. PMID: 25075324 Free PMC article.
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