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Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia.
Science. 2020 Jan 31;367(6477):586-590. doi: 10.1126/science.aax5863.
Science. 2020.
PMID: 32001657
Free PMC article.
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia.
Krivtsov AV, Evans K, Gadrey JY, Eschle BK, Hatton C, Uckelmann HJ, Ross KN, Perner F, Olsen SN, Pritchard T, McDermott L, Jones CD, Jing D, Braytee A, Chacon D, Earley E, McKeever BM, Claremon D, Gifford AJ, Lee HJ, Teicher BA, Pimanda JE, Beck D, Perry JA, Smith MA, McGeehan GM, Lock RB, Armstrong SA.
Krivtsov AV, et al. Among authors: gadrey jy.
Cancer Cell. 2019 Dec 9;36(6):660-673.e11. doi: 10.1016/j.ccell.2019.11.001.
Cancer Cell. 2019.
PMID: 31821784
Free PMC article.
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Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts.
Perner F, Gadrey JY, Xiong Y, Hatton C, Eschle BK, Weiss A, Stauffer F, Gaul C, Tiedt R, Perry JA, Armstrong SA, Krivtsov AV.
Perner F, et al. Among authors: gadrey jy.
Blood. 2020 Oct 22;136(17):1983-1988. doi: 10.1182/blood.2020006113.
Blood. 2020.
PMID: 32575123
Free PMC article.
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