Chu PY - Search Results

1

Improved translation of stability for conjugated antibodies using an in vitro whole blood assay.

Fourie-O'Donohue A, Chu PY, Dela Cruz Chuh J, Tchelepi R, Tsai SP, Tran JC, Sawyer WS, Su D, Ng C, Xu K, Yu SF, Pillow TH, Sadowsky J, Dragovich PS, Liu Y, Kozak KR. Fourie-O'Donohue A, et al. Among authors: chu py. MAbs. 2020 Jan-Dec;12(1):1715705. doi: 10.1080/19420862.2020.1715705. MAbs. 2020. PMID: 31997712 Free PMC article.

2

Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein- and Peptide-Payload Conjugates: Application to THIOMAB Antibody-Drug Conjugates.

Sadowsky JD, Pillow TH, Chen J, Fan F, He C, Wang Y, Yan G, Yao H, Xu Z, Martin S, Zhang D, Chu P, Dela Cruz-Chuh J, O'Donohue A, Li G, Del Rosario G, He J, Liu L, Ng C, Su D, Lewis Phillips GD, Kozak KR, Yu SF, Xu K, Leipold D, Wai J. Sadowsky JD, et al. Bioconjug Chem. 2017 Aug 16;28(8):2086-2098. doi: 10.1021/acs.bioconjchem.7b00258. Epub 2017 Jul 13. Bioconjug Chem. 2017. PMID: 28636382

3

Automated On-tip Affinity Capture Coupled with Mass Spectrometry to Characterize Intact Antibody-Drug Conjugates from Blood.

Li KS, Chu PY, Fourie-O'Donohue A, Srikumar N, Kozak KR, Liu Y, Tran JC. Li KS, et al. Among authors: chu py. J Am Soc Mass Spectrom. 2018 Jul;29(7):1532-1537. doi: 10.1007/s13361-018-1961-7. Epub 2018 May 29. J Am Soc Mass Spectrom. 2018. PMID: 29845559

4

High-throughput antibody screening from complex matrices using intact protein electrospray mass spectrometry.

Sawyer WS, Srikumar N, Carver J, Chu PY, Shen A, Xu A, Williams AJ, Spiess C, Wu C, Liu Y, Tran JC. Sawyer WS, et al. Among authors: chu py. Proc Natl Acad Sci U S A. 2020 May 5;117(18):9851-9856. doi: 10.1073/pnas.1917383117. Epub 2020 Apr 23. Proc Natl Acad Sci U S A. 2020. PMID: 32327606 Free PMC article.

5

Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema.

Agard NJ, Zhang G, Ridgeway J, Dicara DM, Chu PY, Ohri R, Sanowar S, Vernes JM, Chi H, Zhang J, Holz E, Paluch M, He G, Benson Y, Zhang J, Chan P, Tang N, Javale P, Wilson B, Barrett K, Rowntree RK, Hang J, Meng YG, Hass P, Fuh G, Piskol R, Bantseev V, Loyet KM, Tran JC, Wu C, Indjeian VB, Shivva V, Yan M. Agard NJ, et al. Among authors: chu py. Transl Vis Sci Technol. 2022 Oct 3;11(10):27. doi: 10.1167/tvst.11.10.27. Transl Vis Sci Technol. 2022. PMID: 36255358 Free PMC article.

6

Translatability of In Vitro Stress for Predicting Deamidation and Oxidation Biotransformation on Biotherapeutics.

Chu PY, Wang H, Ross E, Stephens N, Zhang HM, Andersen N, Chan W, Shivva V, Crowell SR, Spiess C, Holder PG, Agard NJ, Ji C, Chen J, Sreedhara A, Wang J, Wu C, Liu Y, Tran JC. Chu PY, et al. Anal Chem. 2023 Dec 12;95(49):17957-17961. doi: 10.1021/acs.analchem.3c02133. Epub 2023 Nov 30. Anal Chem. 2023. PMID: 38084380

7

Long-term outcomes from prophylactic or episodic treatment of haemophilia A: A systematic review.

O'Hara J, Sima CS, Frimpter J, Paliargues F, Chu P, Presch I. O'Hara J, et al. Haemophilia. 2018 Sep;24(5):e301-e311. doi: 10.1111/hae.13546. Epub 2018 Jul 13. Haemophilia. 2018. PMID: 30004613

8

Glutathione S-transferase omega class 1 (GSTO1)-associated large extracellular vesicles are involved in tumor-associated macrophage-mediated cisplatin resistance in bladder cancer.

Pan YC, Chu PY, Lin CC, Hsieh CY, Hsu WY, Shyur LF, Yang JC, Chang WC, Wu YC. Pan YC, et al. Among authors: chu py. Mol Oncol. 2024 May 15. doi: 10.1002/1878-0261.13659. Online ahead of print. Mol Oncol. 2024. PMID: 38750006 Free article.

9

Mitochondrial calcium uniporter as biomarker and therapeutic target for breast cancer: Prognostication, immune microenvironment, epigenetic regulation and precision medicine.

Lin HY, Chu PY. Lin HY, et al. Among authors: chu py. J Adv Res. 2024 Apr 24:S2090-1232(24)00158-9. doi: 10.1016/j.jare.2024.04.015. Online ahead of print. J Adv Res. 2024. PMID: 38663838 Free article.

10

Spatial and single-cell explorations uncover prognostic significance and immunological functions of mitochondrial calcium uniporter in breast cancer.

Li CJ, Tzeng YT, Hsiao JH, Tseng LM, Hsu TS, Chu PY. Li CJ, et al. Among authors: chu py. Cancer Cell Int. 2024 Apr 17;24(1):140. doi: 10.1186/s12935-024-03327-z. Cancer Cell Int. 2024. PMID: 38632642 Free PMC article.

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