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Aerosol Delivery of Synthetic mRNA to Vaginal Mucosa Leads to Durable Expression of Broadly Neutralizing Antibodies against HIV.
Lindsay KE, Vanover D, Thoresen M, King H, Xiao P, Badial P, Araínga M, Park SB, Tiwari PM, Peck HE, Blanchard EL, Feugang JM, Olivier AK, Zurla C, Villinger F, Woolums AR, Santangelo PJ. Lindsay KE, et al. Mol Ther. 2020 Mar 4;28(3):805-819. doi: 10.1016/j.ymthe.2020.01.002. Epub 2020 Jan 10. Mol Ther. 2020. PMID: 31995741 Free PMC article.
Early treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection.
Santangelo PJ, Cicala C, Byrareddy SN, Ortiz KT, Little D, Lindsay KE, Gumber S, Hong JJ, Jelicic K, Rogers KA, Zurla C, Villinger F, Ansari AA, Fauci AS, Arthos J. Santangelo PJ, et al. Among authors: lindsay ke. Mucosal Immunol. 2018 May;11(3):932-946. doi: 10.1038/mi.2017.112. Epub 2017 Dec 20. Mucosal Immunol. 2018. PMID: 29346349 Free PMC article.
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver.
Sago CD, Lokugamage MP, Loughrey D, Lindsay KE, Hincapie R, Krupczak BR, Kalathoor S, Sato M, Echeverri ES, Fitzgerald JP, Gan Z, Gamboa L, Paunovska K, Sanhueza CA, Hatit MZC, Finn MG, Santangelo PJ, Dahlman JE. Sago CD, et al. Among authors: lindsay ke. Nat Biomed Eng. 2022 Feb;6(2):157-167. doi: 10.1038/s41551-022-00847-9. Epub 2022 Feb 21. Nat Biomed Eng. 2022. PMID: 35190679
15 results