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Aromatic-Amine Pendants Produce Highly Potent and Efficacious Mixed Efficacy μ-Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Peptidomimetics with Enhanced Metabolic Stability.
J Med Chem. 2020 Feb 27;63(4):1671-1683. doi: 10.1021/acs.jmedchem.9b01818. Epub 2020 Feb 10.
J Med Chem. 2020.
PMID: 31986033
Free PMC article.
SAR Matrices Enable Discovery of Mixed Efficacy μ-Opioid Receptor Agonist Peptidomimetics with Simplified Structures through an Aromatic-Amine Pharmacophore.
Henry S, Anand JP, Brinkel AC, McMillan DM, Twarozynski JJ, Loo CE, Traynor JR, Mosberg HI.
Henry S, et al. Among authors: brinkel ac.
ACS Chem Neurosci. 2021 Jan 6;12(1):216-233. doi: 10.1021/acschemneuro.0c00693. Epub 2020 Dec 21.
ACS Chem Neurosci. 2021.
PMID: 33346631
Free PMC article.
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