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Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair.
Ledbetter MP, Craig JM, Karadeema RJ, Noakes MT, Kim HC, Abell SJ, Huang JR, Anderson BA, Krishnamurthy R, Gundlach JH, Romesberg FE. Ledbetter MP, et al. Among authors: karadeema rj. J Am Chem Soc. 2020 Feb 5;142(5):2110-2114. doi: 10.1021/jacs.9b09808. Epub 2020 Jan 27. J Am Chem Soc. 2020. PMID: 31985216 Free PMC article.
Expansion of the genetic code via expansion of the genetic alphabet.
Dien VT, Morris SE, Karadeema RJ, Romesberg FE. Dien VT, et al. Among authors: karadeema rj. Curr Opin Chem Biol. 2018 Oct;46:196-202. doi: 10.1016/j.cbpa.2018.08.009. Epub 2018 Sep 8. Curr Opin Chem Biol. 2018. PMID: 30205312 Free PMC article. Review.
Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.
Oh J, Shin J, Unarta IC, Wang W, Feldman AW, Karadeema RJ, Xu L, Xu J, Chong J, Krishnamurthy R, Huang X, Romesberg FE, Wang D. Oh J, et al. Among authors: karadeema rj. Nat Chem Biol. 2021 Aug;17(8):906-914. doi: 10.1038/s41589-021-00817-3. Epub 2021 Jun 17. Nat Chem Biol. 2021. PMID: 34140682 Free PMC article.
New codons for efficient production of unnatural proteins in a semisynthetic organism.
Fischer EC, Hashimoto K, Zhang Y, Feldman AW, Dien VT, Karadeema RJ, Adhikary R, Ledbetter MP, Krishnamurthy R, Romesberg FE. Fischer EC, et al. Among authors: karadeema rj. Nat Chem Biol. 2020 May;16(5):570-576. doi: 10.1038/s41589-020-0507-z. Epub 2020 Apr 6. Nat Chem Biol. 2020. PMID: 32251411 Free PMC article.