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Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node.
Li N, Kalyanasundaram A, Hansen BJ, Artiga EJ, Sharma R, Abudulwahed SH, Helfrich KM, Rozenberg G, Wu PJ, Zakharkin S, Gyorke S, Janssen PM, Whitson BA, Mokadam NA, Biesiadecki BJ, Accornero F, Hummel JD, Mohler PJ, Dobrzynski H, Zhao J, Fedorov VV. Li N, et al. Among authors: gyorke s. Nat Commun. 2020 Jan 24;11(1):512. doi: 10.1038/s41467-019-14039-8. Nat Commun. 2020. PMID: 31980605 Free PMC article.
A mutation in calsequestrin, CASQ2D307H, impairs Sarcoplasmic Reticulum Ca2+ handling and causes complex ventricular arrhythmias in mice.
Dirksen WP, Lacombe VA, Chi M, Kalyanasundaram A, Viatchenko-Karpinski S, Terentyev D, Zhou Z, Vedamoorthyrao S, Li N, Chiamvimonvat N, Carnes CA, Franzini-Armstrong C, Györke S, Periasamy M. Dirksen WP, et al. Among authors: gyorke s. Cardiovasc Res. 2007 Jul 1;75(1):69-78. doi: 10.1016/j.cardiores.2007.03.002. Epub 2007 Mar 12. Cardiovasc Res. 2007. PMID: 17449018 Free PMC article.
Effects of dietary omega-3 fatty acids on ventricular function in dogs with healed myocardial infarctions: in vivo and in vitro studies.
Billman GE, Nishijima Y, Belevych AE, Terentyev D, Xu Y, Haizlip KM, Monasky MM, Hiranandani N, Harris WS, Gyorke S, Carnes CA, Janssen PM. Billman GE, et al. Among authors: gyorke s. Am J Physiol Heart Circ Physiol. 2010 Apr;298(4):H1219-28. doi: 10.1152/ajpheart.01065.2009. Epub 2010 Jan 22. Am J Physiol Heart Circ Physiol. 2010. PMID: 20097770 Free PMC article.
Functional consequences of stably expressing a mutant calsequestrin (CASQ2D307H) in the CASQ2 null background.
Kalyanasundaram A, Viatchenko-Karpinski S, Belevych AE, Lacombe VA, Hwang HS, Knollmann BC, Gyorke S, Periasamy M. Kalyanasundaram A, et al. Among authors: gyorke s. Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H253-61. doi: 10.1152/ajpheart.00578.2011. Epub 2011 Oct 7. Am J Physiol Heart Circ Physiol. 2012. PMID: 21984545 Free PMC article.
Up-regulation of sarcoplasmic reticulum Ca(2+) uptake leads to cardiac hypertrophy, contractile dysfunction and early mortality in mice deficient in CASQ2.
Kalyanasundaram A, Lacombe VA, Belevych AE, Brunello L, Carnes CA, Janssen PM, Knollmann BC, Periasamy M, Gyørke S. Kalyanasundaram A, et al. Among authors: gyorke s. Cardiovasc Res. 2013 May 1;98(2):297-306. doi: 10.1093/cvr/cvs334. Epub 2012 Nov 6. Cardiovasc Res. 2013. PMID: 23135969 Free PMC article.
Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.
Brunello L, Slabaugh JL, Radwanski PB, Ho HT, Belevych AE, Lou Q, Chen H, Napolitano C, Lodola F, Priori SG, Fedorov VV, Volpe P, Fill M, Janssen PM, Györke S. Brunello L, et al. Among authors: gyorke s. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10312-7. doi: 10.1073/pnas.1300052110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733959 Free PMC article.
154 results