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118 results

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Page 1
Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node.
Li N, Kalyanasundaram A, Hansen BJ, Artiga EJ, Sharma R, Abudulwahed SH, Helfrich KM, Rozenberg G, Wu PJ, Zakharkin S, Gyorke S, Janssen PM, Whitson BA, Mokadam NA, Biesiadecki BJ, Accornero F, Hummel JD, Mohler PJ, Dobrzynski H, Zhao J, Fedorov VV. Li N, et al. Among authors: dobrzynski h. Nat Commun. 2020 Jan 24;11(1):512. doi: 10.1038/s41467-019-14039-8. Nat Commun. 2020. PMID: 31980605 Free PMC article.
TGF-β1-mediated fibrosis and ion channel remodeling are key mechanisms in producing the sinus node dysfunction associated with SCN5A deficiency and aging.
Hao X, Zhang Y, Zhang X, Nirmalan M, Davies L, Konstantinou D, Yin F, Dobrzynski H, Wang X, Grace A, Zhang H, Boyett M, Huang CL, Lei M. Hao X, et al. Among authors: dobrzynski h. Circ Arrhythm Electrophysiol. 2011 Jun;4(3):397-406. doi: 10.1161/CIRCEP.110.960807. Epub 2011 Apr 14. Circ Arrhythm Electrophysiol. 2011. PMID: 21493874
Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart.
Li N, Csepe TA, Hansen BJ, Dobrzynski H, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Rosen MR, Biesiadecki BJ, Fedorov VV. Li N, et al. Among authors: dobrzynski h. Circ Arrhythm Electrophysiol. 2015 Oct;8(5):1219-27. doi: 10.1161/CIRCEP.115.003070. Epub 2015 Aug 24. Circ Arrhythm Electrophysiol. 2015. PMID: 26304511 Free PMC article.
Silencing miR-370-3p rescues funny current and sinus node function in heart failure.
Yanni J, D'Souza A, Wang Y, Li N, Hansen BJ, Zakharkin SO, Smith M, Hayward C, Whitson BA, Mohler PJ, Janssen PML, Zeef L, Choudhury M, Zi M, Cai X, Logantha SJRJ, Nakao S, Atkinson A, Petkova M, Doris U, Ariyaratnam J, Cartwright EJ, Griffiths-Jones S, Hart G, Fedorov VV, Oceandy D, Dobrzynski H, Boyett MR. Yanni J, et al. Among authors: dobrzynski h. Sci Rep. 2020 Jul 9;10(1):11279. doi: 10.1038/s41598-020-67790-0. Sci Rep. 2020. PMID: 32647133 Free PMC article.
Identification of Key Small Non-Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node.
Petkova M, Atkinson AJ, Yanni J, Stuart L, Aminu AJ, Ivanova AD, Pustovit KB, Geragthy C, Feather A, Li N, Zhang Y, Oceandy D, Perde F, Molenaar P, D'Souza A, Fedorov VV, Dobrzynski H. Petkova M, et al. Among authors: dobrzynski h. J Am Heart Assoc. 2020 Oct 20;9(20):e016590. doi: 10.1161/JAHA.120.016590. Epub 2020 Oct 16. J Am Heart Assoc. 2020. PMID: 33059532 Free PMC article.
Altered microRNA and mRNA profiles during heart failure in the human sinoatrial node.
Li N, Artiga E, Kalyanasundaram A, Hansen BJ, Webb A, Pietrzak M, Biesiadecki B, Whitson B, Mokadam NA, Janssen PML, Hummel JD, Mohler PJ, Dobrzynski H, Fedorov VV. Li N, et al. Among authors: dobrzynski h. Sci Rep. 2021 Sep 29;11(1):19328. doi: 10.1038/s41598-021-98580-x. Sci Rep. 2021. PMID: 34588502 Free PMC article.
118 results