Simon JA - Search Results

1

Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies.

Chowdhury S, Sripathy S, Webster A, Park A, Lao U, Hsu JH, Loe T, Bedalov A, Simon JA. Chowdhury S, et al. Among authors: simon ja. Molecules. 2020 Jan 21;25(3):455. doi: 10.3390/molecules25030455. Molecules. 2020. PMID: 31973227 Free PMC article.

2

Development of pyrazolone and isoxazol-5-one cambinol analogues as sirtuin inhibitors.

Mahajan SS, Scian M, Sripathy S, Posakony J, Lao U, Loe TK, Leko V, Thalhofer A, Schuler AD, Bedalov A, Simon JA. Mahajan SS, et al. Among authors: simon ja. J Med Chem. 2014 Apr 24;57(8):3283-94. doi: 10.1021/jm4018064. Epub 2014 Apr 15. J Med Chem. 2014. PMID: 24697269 Free PMC article.

3

Identification and characterization of small-molecule inhibitors of hepsin.

Chevillet JR, Park GJ, Bedalov A, Simon JA, Vasioukhin VI. Chevillet JR, et al. Among authors: simon ja. Mol Cancer Ther. 2008 Oct;7(10):3343-51. doi: 10.1158/1535-7163.MCT-08-0446. Mol Cancer Ther. 2008. PMID: 18852137 Free PMC article.

4

Sirtuin modulators.

Mahajan SS, Leko V, Simon JA, Bedalov A. Mahajan SS, et al. Among authors: simon ja. Handb Exp Pharmacol. 2011;206:241-55. doi: 10.1007/978-3-642-21631-2_11. Handb Exp Pharmacol. 2011. PMID: 21879453 Free PMC article. Review.

5

Inhibitors of Sir2: evaluation of splitomicin analogues.

Posakony J, Hirao M, Stevens S, Simon JA, Bedalov A. Posakony J, et al. Among authors: simon ja. J Med Chem. 2004 May 6;47(10):2635-44. doi: 10.1021/jm030473r. J Med Chem. 2004. PMID: 15115404

6

Yeast as a model system for anticancer drug discovery.

Simon JA, Bedalov A. Simon JA, et al. Nat Rev Cancer. 2004 Jun;4(6):481-92. doi: 10.1038/nrc1372. Nat Rev Cancer. 2004. PMID: 15170450 Review. No abstract available.

7

Sir2 flexes its muscle.

Bedalov A, Simon JA. Bedalov A, et al. Among authors: simon ja. Dev Cell. 2003 Aug;5(2):188-9. doi: 10.1016/s1534-5807(03)00237-5. Dev Cell. 2003. PMID: 12919668 Free article.

8

Biology, Chemistry, and Pharmacology of Sirtuins.

Bedalov A, Chowdhury S, Simon JA. Bedalov A, et al. Among authors: simon ja. Methods Enzymol. 2016;574:183-211. doi: 10.1016/bs.mie.2016.03.011. Epub 2016 Mar 28. Methods Enzymol. 2016. PMID: 27423863

9

Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes.

Heltweg B, Gatbonton T, Schuler AD, Posakony J, Li H, Goehle S, Kollipara R, Depinho RA, Gu Y, Simon JA, Bedalov A. Heltweg B, et al. Among authors: simon ja. Cancer Res. 2006 Apr 15;66(8):4368-77. doi: 10.1158/0008-5472.CAN-05-3617. Cancer Res. 2006. PMID: 16618762

10

Enterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model.

Leko V, Park GJ, Lao U, Simon JA, Bedalov A. Leko V, et al. Among authors: simon ja. PLoS One. 2013 Jun 14;8(6):e66283. doi: 10.1371/journal.pone.0066283. Print 2013. PLoS One. 2013. PMID: 23799088 Free PMC article.

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