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Didox (3,4-dihydroxybenzohydroxamic acid) reduces the vascular inflammation induced by acute intravascular hemolysis.
Blood Cells Mol Dis. 2020 Mar;81:102404. doi: 10.1016/j.bcmd.2020.102404. Epub 2020 Jan 11.
Blood Cells Mol Dis. 2020.
PMID: 31972517
No abstract available.
Heme induces significant neutrophil adhesion in vitro via an NFκB and reactive oxygen species-dependent pathway.
Miguel LI, Leonardo FC, Torres LS, Garcia F, Mendonça R, Ferreira WA Jr, Gotardo ÉMF, Fabris FCZ, Brito PL, Costa FF, Conran N.
Miguel LI, et al.
Mol Cell Biochem. 2021 Nov;476(11):3963-3974. doi: 10.1007/s11010-021-04210-5. Epub 2021 Jun 30.
Mol Cell Biochem. 2021.
PMID: 34191232
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CXCR4hi effector neutrophils in sickle cell anemia: potential role for elevated circulating serotonin (5-HT) in CXCR4hi neutrophil polarization.
Garcia F, Mendonça R, Miguel LI, Dominical VM, Saad STO, Costa FF, Conran N.
Garcia F, et al. Among authors: miguel li.
Sci Rep. 2020 Aug 31;10(1):14262. doi: 10.1038/s41598-020-71078-8.
Sci Rep. 2020.
PMID: 32868775
Free PMC article.
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Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease Are Amplified by Hydroxyurea: In Vitro and In Vivo Studies.
Ferreira WA Jr, Chweih H, Lanaro C, Almeida CB, Brito PL, Gotardo EMF, Torres L, Miguel LI, Franco-Penteado CF, Leonardo FC, Garcia F, Saad STO, Frenette PS, Brockschnieder D, Costa FF, Stasch JP, Sandner P, Conran N.
Ferreira WA Jr, et al. Among authors: miguel li.
J Pharmacol Exp Ther. 2020 Sep;374(3):469-478. doi: 10.1124/jpet.119.264606. Epub 2020 Jul 6.
J Pharmacol Exp Ther. 2020.
PMID: 32631869
Free PMC article.
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Inhibition of phosphodiesterase 9A reduces cytokine-stimulated in vitro adhesion of neutrophils from sickle cell anemia individuals.
Miguel LI, Almeida CB, Traina F, Canalli AA, Dominical VM, Saad ST, Costa FF, Conran N.
Miguel LI, et al.
Inflamm Res. 2011 Jul;60(7):633-42. doi: 10.1007/s00011-011-0315-8. Epub 2011 Feb 20.
Inflamm Res. 2011.
PMID: 21336703
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Neutrophils of rheumatoid arthritis patients on anti-TNF-α therapy and in disease remission present reduced adhesive functions in association with decreased circulating neutrophil-attractant chemokine levels.
Dominical VM, Bértolo MB, Almeida CB, Garrido VT, Miguel LI, Costa FF, Conran N.
Dominical VM, et al. Among authors: miguel li.
Scand J Immunol. 2011 Apr;73(4):309-18. doi: 10.1111/j.1365-3083.2011.02503.x.
Scand J Immunol. 2011.
PMID: 21208248
Free article.
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