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Page 1
Clinical implications of intratumor heterogeneity: challenges and opportunities.
Ramón Y Cajal S, Sesé M, Capdevila C, Aasen T, De Mattos-Arruda L, Diaz-Cano SJ, Hernández-Losa J, Castellví J. Ramón Y Cajal S, et al. J Mol Med (Berl). 2020 Feb;98(2):161-177. doi: 10.1007/s00109-020-01874-2. Epub 2020 Jan 22. J Mol Med (Berl). 2020. PMID: 31970428 Free PMC article. Review.
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.
De Mattos-Arruda L, Mayor R, Ng CKY, Weigelt B, Martínez-Ricarte F, Torrejon D, Oliveira M, Arias A, Raventos C, Tang J, Guerini-Rocco E, Martínez-Sáez E, Lois S, Marín O, de la Cruz X, Piscuoglio S, Towers R, Vivancos A, Peg V, Ramon y Cajal S, Carles J, Rodon J, González-Cao M, Tabernero J, Felip E, Sahuquillo J, Berger MF, Cortes J, Reis-Filho JS, Seoane J. De Mattos-Arruda L, et al. Nat Commun. 2015 Nov 10;6:8839. doi: 10.1038/ncomms9839. Nat Commun. 2015. PMID: 26554728 Free PMC article.
Cancer as an ecomolecular disease and a neoplastic consortium.
Ramón Y Cajal S, Capdevila C, Hernandez-Losa J, De Mattos-Arruda L, Ghosh A, Lorent J, Larsson O, Aasen T, Postovit LM, Topisirovic I. Ramón Y Cajal S, et al. Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):484-499. doi: 10.1016/j.bbcan.2017.09.004. Epub 2017 Sep 23. Biochim Biophys Acta Rev Cancer. 2017. PMID: 28947238 Review.
Genetic heterogeneity and actionable mutations in HER2-positive primary breast cancers and their brain metastases.
De Mattos-Arruda L, Ng CKY, Piscuoglio S, Gonzalez-Cao M, Lim RS, De Filippo MR, Fusco N, Schultheis AM, Ortiz C, Viteri S, Arias A, Macedo GS, Oliveira M, Gomez P, Teixidó C, Nuciforo P, Peg V, Saura C, Ramon Y Cajal S, Casas FT, Weigelt B, Cortes J, Seoane J, Reis-Filho JS. De Mattos-Arruda L, et al. Oncotarget. 2018 Apr 17;9(29):20617-20630. doi: 10.18632/oncotarget.25041. eCollection 2018 Apr 17. Oncotarget. 2018. PMID: 29755676 Free PMC article.
The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer.
De Mattos-Arruda L, Sammut SJ, Ross EM, Bashford-Rogers R, Greenstein E, Markus H, Morganella S, Teng Y, Maruvka Y, Pereira B, Rueda OM, Chin SF, Contente-Cuomo T, Mayor R, Arias A, Ali HR, Cope W, Tiezzi D, Dariush A, Dias Amarante T, Reshef D, Ciriaco N, Martinez-Saez E, Peg V, Ramon Y Cajal S, Cortes J, Vassiliou G, Getz G, Nik-Zainal S, Murtaza M, Friedman N, Markowetz F, Seoane J, Caldas C. De Mattos-Arruda L, et al. Cell Rep. 2019 May 28;27(9):2690-2708.e10. doi: 10.1016/j.celrep.2019.04.098. Cell Rep. 2019. PMID: 31141692 Free PMC article.
Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.
De Mattos-Arruda L, Weigelt B, Cortes J, Won HH, Ng CKY, Nuciforo P, Bidard FC, Aura C, Saura C, Peg V, Piscuoglio S, Oliveira M, Smolders Y, Patel P, Norton L, Tabernero J, Berger MF, Seoane J, Reis-Filho JS. De Mattos-Arruda L, et al. Ann Oncol. 2014 Sep;25(9):1729-1735. doi: 10.1093/annonc/mdu239. Epub 2014 Jul 9. Ann Oncol. 2014. PMID: 25009010 Free PMC article. Clinical Trial.
60 results