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The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas.
Gargini R, Segura-Collar B, Herránz B, García-Escudero V, Romero-Bravo A, Núñez FJ, García-Pérez D, Gutiérrez-Guamán J, Ayuso-Sacido A, Seoane J, Pérez-Núñez A, Sepúlveda-Sánchez JM, Hernández-Laín A, Castro MG, García-Escudero R, Ávila J, Sánchez-Gómez P. Gargini R, et al. Sci Transl Med. 2020 Jan 22;12(527):eaax1501. doi: 10.1126/scitranslmed.aax1501. Sci Transl Med. 2020. PMID: 31969485 Free PMC article.
Tau mRNA 3'UTR-to-CDS ratio is increased in Alzheimer disease.
García-Escudero V, Gargini R, Martín-Maestro P, García E, García-Escudero R, Avila J. García-Escudero V, et al. Neurosci Lett. 2017 Aug 10;655:101-108. doi: 10.1016/j.neulet.2017.07.007. Epub 2017 Jul 8. Neurosci Lett. 2017. PMID: 28689927 Free article.
A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer's disease.
García-Escudero V, Ruiz-Gabarre D, Gargini R, Pérez M, García E, Cuadros R, Hernández IH, Cabrera JR, García-Escudero R, Lucas JJ, Hernández F, Ávila J. García-Escudero V, et al. Among authors: garcia escudero r. Acta Neuropathol. 2021 Jul;142(1):159-177. doi: 10.1007/s00401-021-02317-z. Epub 2021 May 2. Acta Neuropathol. 2021. PMID: 33934221 Free PMC article.
EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours.
Bornachea O, Santos M, Martínez-Cruz AB, García-Escudero R, Dueñas M, Costa C, Segrelles C, Lorz C, Buitrago A, Saiz-Ladera C, Agirre X, Grande T, Paradela B, Maraver A, Ariza JM, Prosper F, Serrano M, Sánchez-Céspedes M, Paramio JM. Bornachea O, et al. Sci Rep. 2012;2:434. doi: 10.1038/srep00434. Epub 2012 May 31. Sci Rep. 2012. PMID: 22666537 Free PMC article.
Bosutinib Inhibits EGFR Activation in Head and Neck Cancer.
Segrelles C, Contreras D, Navarro EM, Gutiérrez-Muñoz C, García-Escudero R, Paramio JM, Lorz C. Segrelles C, et al. Int J Mol Sci. 2018 Jun 21;19(7):1824. doi: 10.3390/ijms19071824. Int J Mol Sci. 2018. PMID: 29933569 Free PMC article.
A Polycomb-mir200 loop regulates clinical outcome in bladder cancer.
Martínez-Fernández M, Dueñas M, Feber A, Segovia C, García-Escudero R, Rubio C, López-Calderón FF, Díaz-García C, Villacampa F, Duarte J, Gómez-Rodriguez MJ, Castellano D, Rodriguez-Peralto JL, de la Rosa F, Beck S, Paramio JM. Martínez-Fernández M, et al. Oncotarget. 2015 Dec 8;6(39):42258-75. doi: 10.18632/oncotarget.5546. Oncotarget. 2015. PMID: 26517683 Free PMC article.
p107 acts as a tumor suppressor in pRb-deficient epidermis.
Lara MF, Santos M, Ruiz S, Segrelles C, Moral M, Martínez-Cruz AB, Hernández P, Martínez-Palacio J, Lorz C, García-Escudero R, Paramio JM. Lara MF, et al. Mol Carcinog. 2008 Feb;47(2):105-13. doi: 10.1002/mc.20367. Mol Carcinog. 2008. PMID: 17932945
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