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ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.
Rafn B, Nielsen CF, Andersen SH, Szyniarowski P, Corcelle-Termeau E, Valo E, Fehrenbacher N, Olsen CJ, Daugaard M, Egebjerg C, Bøttzauw T, Kohonen P, Nylandsted J, Hautaniemi S, Moreira J, Jäättelä M, Kallunki T. Rafn B, et al. Among authors: kallunki t. Mol Cell. 2012 Mar 30;45(6):764-76. doi: 10.1016/j.molcel.2012.01.029. Mol Cell. 2012. PMID: 22464443 Free article.
Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion.
Brix DM, Tvingsholm SA, Hansen MB, Clemmensen KB, Ohman T, Siino V, Lambrughi M, Hansen K, Puustinen P, Gromova I, James P, Papaleo E, Varjosalo M, Moreira J, Jäättelä M, Kallunki T. Brix DM, et al. Among authors: kallunki t. Oncogene. 2019 Apr;38(17):3170-3184. doi: 10.1038/s41388-018-0653-x. Epub 2019 Jan 8. Oncogene. 2019. PMID: 30622337 Free PMC article.
Cancer-associated lysosomal changes: friends or foes?
Kallunki T, Olsen OD, Jäättelä M. Kallunki T, et al. Oncogene. 2013 Apr 18;32(16):1995-2004. doi: 10.1038/onc.2012.292. Epub 2012 Jul 9. Oncogene. 2013. PMID: 22777359 Review.
51 results