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Probing biological mechanisms with chemical tools.
Kang C, Keller TH. Kang C, et al. Among authors: keller th. Pharmacol Res. 2020 Mar;153:104656. doi: 10.1016/j.phrs.2020.104656. Epub 2020 Jan 18. Pharmacol Res. 2020. PMID: 31962154 Review.
Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Anantharajan J, Zhou H, Zhang L, Hotz T, Vincent MY, Blevins MA, Jansson AE, Kuan JWL, Ng EY, Yeo YK, Baburajendran N, Lin G, Hung AW, Joy J, Patnaik S, Marugan J, Rudra P, Ghosh D, Hill J, Keller TH, Zhao R, Ford HL, Kang C. Anantharajan J, et al. Among authors: keller th. Mol Cancer Ther. 2019 Sep;18(9):1484-1496. doi: 10.1158/1535-7163.MCT-18-1239. Epub 2019 Jul 8. Mol Cancer Ther. 2019. PMID: 31285279 Free PMC article.
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.
Anantharajan J, Baburajendran N, Lin G, Loh YY, Xu W, Ahmad NHB, Liu S, Jansson AE, Kuan JWL, Ng EY, Yeo YK, Hung AW, Joy J, Hill J, Ford HL, Zhao R, Keller TH, Kang C. Anantharajan J, et al. Among authors: keller th. Protein Sci. 2022 Feb;31(2):422-431. doi: 10.1002/pro.4234. Epub 2021 Nov 18. Protein Sci. 2022. PMID: 34761455 Free PMC article.
Zika Virus Protease: An Antiviral Drug Target.
Kang C, Keller TH, Luo D. Kang C, et al. Among authors: keller th. Trends Microbiol. 2017 Oct;25(10):797-808. doi: 10.1016/j.tim.2017.07.001. Epub 2017 Aug 5. Trends Microbiol. 2017. PMID: 28789826 Review.
94 results