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The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling.
J Biol Chem. 2020 Feb 28;295(9):2866-2884. doi: 10.1074/jbc.RA119.010077. Epub 2020 Jan 20.
J Biol Chem. 2020.
PMID: 31959628
Free PMC article.
A C-terminal cysteine residue is required for peptide-based inhibition of the NGF/TrkA interaction at nM concentrations: implications for peptide-based analgesics.
Poole AJ, Frigotto L, Smith ME, Baar C, Ivanova-Berndt G, Jaulent A, Stace C, Ullman CG, Hine AV.
Poole AJ, et al. Among authors: ivanova berndt g.
Sci Rep. 2019 Jan 30;9(1):930. doi: 10.1038/s41598-018-37585-5.
Sci Rep. 2019.
PMID: 30700786
Free PMC article.
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Discovery of BT8009: A Nectin-4 Targeting Bicycle Toxin Conjugate for the Treatment of Cancer.
Mudd GE, Scott H, Chen L, van Rietschoten K, Ivanova-Berndt G, Dzionek K, Brown A, Watcham S, White L, Park PU, Jeffrey P, Rigby M, Beswick P.
Mudd GE, et al. Among authors: ivanova berndt g.
J Med Chem. 2022 Nov 10;65(21):14337-14347. doi: 10.1021/acs.jmedchem.2c00065. Epub 2022 Oct 6.
J Med Chem. 2022.
PMID: 36204777
Free PMC article.
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An Assay for Periplasm Entry Advances the Development of Chimeric Peptide Antibiotics.
Wagstaff JM, Balmforth M, Lewis N, Dods R, Rowland C, van Rietschoten K, Chen L, Harrison H, Skynner MJ, Dawson M, Ivanova-Berndt G, Beswick P.
Wagstaff JM, et al. Among authors: ivanova berndt g.
ACS Infect Dis. 2020 Sep 11;6(9):2355-2361. doi: 10.1021/acsinfecdis.0c00389. Epub 2020 Aug 15.
ACS Infect Dis. 2020.
PMID: 32697574
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