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Computational polypharmacology: a new paradigm for drug discovery.
Chaudhari R, Tan Z, Huang B, Zhang S. Chaudhari R, et al. Among authors: zhang s. Expert Opin Drug Discov. 2017 Mar;12(3):279-291. doi: 10.1080/17460441.2017.1280024. Epub 2017 Jan 23. Expert Opin Drug Discov. 2017. PMID: 28067061 Free PMC article. Review.
OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers.
Monroig-Bosque PDC, Shah MY, Fu X, Fuentes-Mattei E, Ling H, Ivan C, Nouraee N, Huang B, Chen L, Pileczki V, Redis RS, Jung EJ, Zhang X, Lehrer M, Nagvekar R, Mafra ACP, Monroig-Bosque MDM, Irimie A, Rivera C, Dan Dumitru C, Berindan-Neagoe I, Nikonowicz EP, Zhang S, Calin GA. Monroig-Bosque PDC, et al. Among authors: zhang s, zhang x. Sci Rep. 2018 Aug 30;8(1):13106. doi: 10.1038/s41598-018-30989-3. Sci Rep. 2018. PMID: 30166612 Free PMC article.
Caspase-3 Substrates for Noninvasive Pharmacodynamic Imaging of Apoptosis by PET/CT.
Engel BJ, Gammon ST, Chaudhari R, Lu Z, Pisaneschi F, Yang H, Ornelas A, Yan V, Kelderhouse L, Najjar AM, Tong WP, Zhang S, Piwnica-Worms D, Bast RC Jr, Millward SW. Engel BJ, et al. Among authors: zhang s. Bioconjug Chem. 2018 Sep 19;29(9):3180-3195. doi: 10.1021/acs.bioconjchem.8b00514. Epub 2018 Aug 31. Bioconjug Chem. 2018. PMID: 30168713 Free PMC article.
Conversion of RNA Aptamer into Modified DNA Aptamers Provides for Prolonged Stability and Enhanced Antitumor Activity.
Amero P, Lokesh GLR, Chaudhari RR, Cardenas-Zuniga R, Schubert T, Attia YM, Montalvo-Gonzalez E, Elsayed AM, Ivan C, Wang Z, Cristini V, Franciscis V, Zhang S, Volk DE, Mitra R, Rodriguez-Aguayo C, Sood AK, Lopez-Berestein G. Amero P, et al. Among authors: zhang s. J Am Chem Soc. 2021 May 26;143(20):7655-7670. doi: 10.1021/jacs.9b10460. Epub 2021 May 14. J Am Chem Soc. 2021. PMID: 33988982
Directed evolution of cyclic peptides for inhibition of autophagy.
Gray JP, Uddin MN, Chaudhari R, Sutton MN, Yang H, Rask P, Locke H, Engel BJ, Batistatou N, Wang J, Grindel BJ, Bhattacharya P, Gammon ST, Zhang S, Piwnica-Worms D, Kritzer JA, Lu Z, Bast RC Jr, Millward SW. Gray JP, et al. Among authors: zhang s. Chem Sci. 2021 Jan 13;12(10):3526-3543. doi: 10.1039/d0sc03603j. Chem Sci. 2021. PMID: 34163626 Free PMC article.
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