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Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis.
J Med Chem. 2020 Apr 23;63(8):3868-3880. doi: 10.1021/acs.jmedchem.9b01621. Epub 2020 Feb 5.
J Med Chem. 2020.
PMID: 31940200
Application of Transition-Metal Catalysis, Biocatalysis, and Flow Chemistry as State-of-the-Art Technologies in the Synthesis of LCZ696.
Gu X, Zhao J, Chen L, Li Y, Yu B, Tian X, Min Z, Xu S, Gu H, Sun J, Lu X, Chang M, Wang X, Zhao L, Ye S, Yang H, Tian Y, Gao F, Gai Y, Jia G, Wu J, Wang Y, Zhang J, Zhang X, Liu W, Gu X, Luo X, Dong H, Wang H, Schenkel B, Venturoni F, Filipponi P, Guelat B, Allmendinger T, Wietfeld B, Hoehn P, Kovacic N, Hermann L, Schlama T, Ruch T, Derrien N, Piechon P, Kleinbeck F.
Gu X, et al. Among authors: schlama t.
J Org Chem. 2020 Jun 5;85(11):6844-6853. doi: 10.1021/acs.joc.0c00473. Epub 2020 May 15.
J Org Chem. 2020.
PMID: 32412751
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Fostering Research Synergies between Chemists in Swiss Academia and at Novartis.
Meyer A, Baeschlin D, Brocklehurst CE, Duckely M, Gallou F, Lovelle LE, Parmentier M, Schlama T, Snajdrova R, Auberson YP.
Meyer A, et al. Among authors: schlama t.
Chimia (Aarau). 2021 Nov 24;75(11):936-942. doi: 10.2533/chimia.2021.936.
Chimia (Aarau). 2021.
PMID: 34798915
Free article.
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Synthetic studies on (-)-lemonomycin: an efficient asymmetric synthesis of lemonomycinone amide.
Wu YC, Bernadat G, Masson G, Couturier C, Schlama T, Zhu J.
Wu YC, et al. Among authors: schlama t.
J Org Chem. 2009 Mar 6;74(5):2046-52. doi: 10.1021/jo8027449.
J Org Chem. 2009.
PMID: 19196163
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Aziridinium from N,N-dibenzyl serine methyl ester: synthesis of enantiomerically pure beta-amino and alpha,beta-diamino esters.
Couturier C, Blanchet J, Schlama T, Zhu J.
Couturier C, et al. Among authors: schlama t.
Org Lett. 2006 May 11;8(10):2183-6. doi: 10.1021/ol060700u.
Org Lett. 2006.
PMID: 16671812
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Suzuki-miyaura coupling of alkynylboronic esters generated in situ from acetylenic derivatives.
Castanet AS, Colobert F, Schlama T.
Castanet AS, et al. Among authors: schlama t.
Org Lett. 2000 Nov 16;2(23):3559-61. doi: 10.1021/ol006439d.
Org Lett. 2000.
PMID: 11073644
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Total Synthesis of (±)-Halomon by a Johnson-Claisen Rearrangement.
Schlama T, Baati R, Gouverneur V, Valleix A, Falck JR, Mioskowski C.
Schlama T, et al.
Angew Chem Int Ed Engl. 1998 Aug 17;37(15):2085-2087. doi: 10.1002/(SICI)1521-3773(19980817)37:15<2085::AID-ANIE2085>3.0.CO;2-J.
Angew Chem Int Ed Engl. 1998.
PMID: 29711050
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Evolution of Biocatalysis at Novartis over the last 40 Years.
Siirola E, Eggimann F, Moore C, Schroer K, Vargas A, Peschke T, Schlama T, Snajdrova R.
Siirola E, et al. Among authors: schlama t.
Chimia (Aarau). 2023 Jun 28;77(6):376-383. doi: 10.2533/chimia.2023.376.
Chimia (Aarau). 2023.
PMID: 38047776
Free article.
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