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Lipid droplets can promote drug accumulation and activation.
Dubey R, Stivala CE, Nguyen HQ, Goo YH, Paul A, Carette JE, Trost BM, Rohatgi R. Dubey R, et al. Among authors: carette je. Nat Chem Biol. 2020 Feb;16(2):206-213. doi: 10.1038/s41589-019-0447-7. Epub 2020 Jan 13. Nat Chem Biol. 2020. PMID: 31932720 Free PMC article.
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.
Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Deans RM, et al. Among authors: carette je. Nat Chem Biol. 2016 May;12(5):361-6. doi: 10.1038/nchembio.2050. Epub 2016 Mar 28. Nat Chem Biol. 2016. PMID: 27018887 Free PMC article.
R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling.
Dubey R, van Kerkhof P, Jordens I, Malinauskas T, Pusapati GV, McKenna JK, Li D, Carette JE, Ho M, Siebold C, Maurice M, Lebensohn AM, Rohatgi R. Dubey R, et al. Among authors: carette je. Elife. 2020 May 20;9:e54469. doi: 10.7554/eLife.54469. Elife. 2020. PMID: 32432544 Free PMC article.
An essential receptor for adeno-associated virus infection.
Pillay S, Meyer NL, Puschnik AS, Davulcu O, Diep J, Ishikawa Y, Jae LT, Wosen JE, Nagamine CM, Chapman MS, Carette JE. Pillay S, et al. Among authors: carette je. Nature. 2016 Feb 4;530(7588):108-12. doi: 10.1038/nature16465. Epub 2016 Jan 27. Nature. 2016. PMID: 26814968 Free PMC article.
PLA2G16 represents a switch between entry and clearance of Picornaviridae.
Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR. Staring J, et al. Among authors: carette je. Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11. Nature. 2017. PMID: 28077878
Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens.
Khodadoust MS, Olsson N, Wagar LE, Haabeth OA, Chen B, Swaminathan K, Rawson K, Liu CL, Steiner D, Lund P, Rao S, Zhang L, Marceau C, Stehr H, Newman AM, Czerwinski DK, Carlton VE, Moorhead M, Faham M, Kohrt HE, Carette J, Green MR, Davis MM, Levy R, Elias JE, Alizadeh AA. Khodadoust MS, et al. Among authors: carette j. Nature. 2017 Mar 30;543(7647):723-727. doi: 10.1038/nature21433. Epub 2017 Mar 22. Nature. 2017. PMID: 28329770 Free PMC article.
112 results