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Development of novel small molecules for the treatment of ALS.
Mathew B, Ruiz P, Pathak V, Suto MJ. Mathew B, et al. Among authors: ruiz p. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126950. doi: 10.1016/j.bmcl.2020.126950. Epub 2020 Jan 7. Bioorg Med Chem Lett. 2020. PMID: 31928838
Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals.
Yatchang MF, Mathew B, Srivastava RK, Khan J, Muzaffar S, Zhang S, Wu M, Zhai L, Ruiz P, Agarwal A, Bostwick JR, Suto MJ, Athar M, Augelli-Szafran CE. Yatchang MF, et al. Among authors: ruiz p. Bioorg Med Chem Lett. 2022 May 15;64:128696. doi: 10.1016/j.bmcl.2022.128696. Epub 2022 Mar 19. Bioorg Med Chem Lett. 2022. PMID: 35318165 Free PMC article.
Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability.
Roth JR, Rush T, Thompson SJ, Aldaher AR, Dunn TB, Mesina JS, Cochran JN, Boyle NR, Dean HB, Yang Z, Pathak V, Ruiz P, Wu M, Day JJ, Bostwick JR, Suto MJ, Augelli-Szafran CE, Roberson ED. Roth JR, et al. Among authors: ruiz p. Neurotherapeutics. 2024 Jan;21(1):e00291. doi: 10.1016/j.neurot.2023.10.001. Epub 2023 Dec 19. Neurotherapeutics. 2024. PMID: 38241154 Free PMC article.
High-Throughput cell-based immunofluorescence assays against influenza.
Martinez-Gzegozewska Y, Rasmussen L, McKellip S, Manuvakhova A, Nebane NM, Reece AJ, Ruiz P, Sosa M, Bostwick R, Vinson P. Martinez-Gzegozewska Y, et al. Among authors: ruiz p. SLAS Discov. 2024 Jan;29(1):66-76. doi: 10.1016/j.slasd.2023.10.008. Epub 2023 Nov 2. SLAS Discov. 2024. PMID: 37925159 Free PMC article.
A High-throughput Response to the SARS-CoV-2 Pandemic.
Rasmussen L, Sanders S, Sosa M, McKellip S, Nebane NM, Martinez-Gzegozewska Y, Reece A, Ruiz P, Manuvakhova A, Zhai L, Warren B, Curry A, Zeng Q, Bostwick JR, Vinson PN. Rasmussen L, et al. Among authors: ruiz p. SLAS Discov. 2024 May 16:100160. doi: 10.1016/j.slasd.2024.100160. Online ahead of print. SLAS Discov. 2024. PMID: 38761981 Free article.
Value contribution of blood-based neurofilament light chain as a biomarker in multiple sclerosis using multi-criteria decision analysis.
Monreal E, Ruiz PD, San Román IL, Rodríguez-Antigüedad A, Moya-Molina MÁ, Álvarez A, García-Arcelay E, Maurino J, Shepherd J, Cabrera ÁP, Villar LM. Monreal E, et al. Among authors: ruiz pd. Front Public Health. 2024 Apr 22;12:1397845. doi: 10.3389/fpubh.2024.1397845. eCollection 2024. Front Public Health. 2024. PMID: 38711771 Free PMC article.
1,308 results