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Expression of human thrombomodulin on porcine endothelial cells can reduce platelet aggregation but did not reduce activation of complement or endothelium - an experimental study.
Ramackers W, Rataj D, Werwitzke S, Bergmann S, Winkler M, Wünsch A, Bähr A, Wolf E, Klymiuk N, Ayares D, Tiede A. Ramackers W, et al. Among authors: winkler m. Transpl Int. 2020 Apr;33(4):437-449. doi: 10.1111/tri.13573. Epub 2020 Feb 9. Transpl Int. 2020. PMID: 31926034 Free article.
Recombinant human antithrombin prevents xenogenic activation of hemostasis in a model of pig-to-human kidney transplantation.
Ramackers W, Friedrich L, Klose J, Vondran F, Bergmann S, Schüttler W, Johanning K, Werwitzke S, Trummer A, Bröcker V, Klempnauer J, Winkler M, Tiede A. Ramackers W, et al. Among authors: winkler m. Xenotransplantation. 2014 Jul-Aug;21(4):367-75. doi: 10.1111/xen.12104. Epub 2014 May 8. Xenotransplantation. 2014. PMID: 24807299
Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys.
Petersen B, Ramackers W, Lucas-Hahn A, Lemme E, Hassel P, Queisser AL, Herrmann D, Barg-Kues B, Carnwath JW, Klose J, Tiede A, Friedrich L, Baars W, Schwinzer R, Winkler M, Niemann H. Petersen B, et al. Among authors: winkler m. Xenotransplantation. 2011 Nov-Dec;18(6):355-68. doi: 10.1111/j.1399-3089.2011.00674.x. Xenotransplantation. 2011. PMID: 22168142
Kidneys From α1,3-Galactosyltransferase Knockout/Human Heme Oxygenase-1/Human A20 Transgenic Pigs Are Protected From Rejection During Ex Vivo Perfusion With Human Blood.
Ahrens HE, Petersen B, Ramackers W, Petkov S, Herrmann D, Hauschild-Quintern J, Lucas-Hahn A, Hassel P, Ziegler M, Baars W, Bergmann S, Schwinzer R, Winkler M, Niemann H. Ahrens HE, et al. Among authors: winkler m. Transplant Direct. 2015 Jul 28;1(6):e23. doi: 10.1097/TXD.0000000000000533. eCollection 2015 Jul. Transplant Direct. 2015. PMID: 27500225 Free PMC article.
1,751 results