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Expression of human thrombomodulin on porcine endothelial cells can reduce platelet aggregation but did not reduce activation of complement or endothelium - an experimental study.
Ramackers W, Rataj D, Werwitzke S, Bergmann S, Winkler M, Wünsch A, Bähr A, Wolf E, Klymiuk N, Ayares D, Tiede A. Ramackers W, et al. Among authors: klymiuk n. Transpl Int. 2020 Apr;33(4):437-449. doi: 10.1111/tri.13573. Epub 2020 Feb 9. Transpl Int. 2020. PMID: 31926034 Free article.
Transgenic pigs as models for translational biomedical research.
Aigner B, Renner S, Kessler B, Klymiuk N, Kurome M, Wünsch A, Wolf E. Aigner B, et al. Among authors: klymiuk n. J Mol Med (Berl). 2010 Jul;88(7):653-64. doi: 10.1007/s00109-010-0610-9. Epub 2010 Mar 26. J Mol Med (Berl). 2010. PMID: 20339830 Review.
First inducible transgene expression in porcine large animal models.
Klymiuk N, Böcker W, Schönitzer V, Bähr A, Radic T, Fröhlich T, Wünsch A, Keßler B, Kurome M, Schilling E, Herbach N, Wanke R, Nagashima H, Mutschler W, Arnold GJ, Schwinzer R, Schieker M, Wolf E. Klymiuk N, et al. FASEB J. 2012 Mar;26(3):1086-99. doi: 10.1096/fj.11-185041. Epub 2011 Dec 1. FASEB J. 2012. PMID: 22138035
Permanent neonatal diabetes in INS(C94Y) transgenic pigs.
Renner S, Braun-Reichhart C, Blutke A, Herbach N, Emrich D, Streckel E, Wünsch A, Kessler B, Kurome M, Bähr A, Klymiuk N, Krebs S, Puk O, Nagashima H, Graw J, Blum H, Wanke R, Wolf E. Renner S, et al. Among authors: klymiuk n. Diabetes. 2013 May;62(5):1505-11. doi: 10.2337/db12-1065. Epub 2012 Dec 28. Diabetes. 2013. PMID: 23274907 Free PMC article.
Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs.
Wuensch A, Baehr A, Bongoni AK, Kemter E, Blutke A, Baars W, Haertle S, Zakhartchenko V, Kurome M, Kessler B, Faber C, Abicht JM, Reichart B, Wanke R, Schwinzer R, Nagashima H, Rieben R, Ayares D, Wolf E, Klymiuk N. Wuensch A, et al. Among authors: klymiuk n. Transplantation. 2014 Jan 27;97(2):138-47. doi: 10.1097/TP.0b013e3182a95cbc. Transplantation. 2014. PMID: 24150517 Free article.
One-year heterotopic cardiac xenograft survival in a pig to baboon model.
Mohiuddin MM, Singh AK, Corcoran PC, Hoyt RF, Thomas ML 3rd, Lewis BG, Eckhaus M, Reimann KA, Klymiuk N, Wolf E, Ayares D, Horvath KA. Mohiuddin MM, et al. Among authors: klymiuk n. Am J Transplant. 2014 Feb;14(2):488-9. doi: 10.1111/ajt.12562. Epub 2013 Dec 11. Am J Transplant. 2014. PMID: 24330419 Free PMC article. No abstract available.
99 results