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The motif EXEXXXL in the cytosolic tail of the secretory human proprotein convertase PC7 regulates its trafficking and cleavage activity.
J Biol Chem. 2020 Feb 14;295(7):2068-2083. doi: 10.1074/jbc.RA119.011775. Epub 2020 Jan 8.
J Biol Chem. 2020.
PMID: 31915245
Free PMC article.
Increasing C-Terminal Hydrophobicity Improves the Cell Permeability and Antiproliferative Activity of PACE4 Inhibitors against Prostate Cancer Cell Lines.
Dianati V, Kwiatkowska A, Couture F, Desjardins R, Dory YL, Day R.
Dianati V, et al.
J Med Chem. 2018 Sep 27;61(18):8457-8467. doi: 10.1021/acs.jmedchem.8b01144. Epub 2018 Sep 17.
J Med Chem. 2018.
PMID: 30180568
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Rational Design of a Highly Potent and Selective Peptide Inhibitor of PACE4 by Salt Bridge Interaction with D160 at Position P3.
Dianati V, Shamloo A, Kwiatkowska A, Desjardins R, Soldera A, Day R, Dory YL.
Dianati V, et al.
ChemMedChem. 2017 Aug 8;12(15):1169-1172. doi: 10.1002/cmdc.201700300. Epub 2017 Jul 19.
ChemMedChem. 2017.
PMID: 28722823
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Improving the Selectivity of PACE4 Inhibitors through Modifications of the P1 Residue.
Dianati V, Navals P, Couture F, Desjardins R, Dame A, Kwiatkowska A, Day R, Dory YL.
Dianati V, et al.
J Med Chem. 2018 Dec 27;61(24):11250-11260. doi: 10.1021/acs.jmedchem.8b01381. Epub 2018 Dec 13.
J Med Chem. 2018.
PMID: 30501188
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Nitric oxide mediates the anticonvulsant effects of thalidomide on pentylenetetrazole-induced clonic seizures in mice.
Payandemehr B, Rahimian R, Gooshe M, Bahremand A, Gholizadeh R, Berijani S, Ahmadi-Dastgerdi M, Aminizade M, Sarreshte-Dari A, Dianati V, Amanlou M, Dehpour AR.
Payandemehr B, et al. Among authors: dianati v.
Epilepsy Behav. 2014 May;34:99-104. doi: 10.1016/j.yebeh.2014.03.020. Epub 2014 Apr 14.
Epilepsy Behav. 2014.
PMID: 24735834
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