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Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells.
Fernández MM, Ferragut F, Cárdenas Delgado VM, Bracalente C, Bravo AI, Cagnoni AJ, Nuñez M, Morosi LG, Quinta HR, Espelt MV, Troncoso MF, Wolfenstein-Todel C, Mariño KV, Malchiodi EL, Rabinovich GA, Elola MT. Fernández MM, et al. Among authors: cagnoni aj. Biochim Biophys Acta. 2016 Oct;1860(10):2255-68. doi: 10.1016/j.bbagen.2016.04.019. Epub 2016 Apr 26. Biochim Biophys Acta. 2016. PMID: 27130882
Dual knockdown of Galectin-8 and its glycosylated ligand, the activated leukocyte cell adhesion molecule (ALCAM/CD166), synergistically delays in vivo breast cancer growth.
Ferragut F, Cagnoni AJ, Colombo LL, Sánchez Terrero C, Wolfenstein-Todel C, Troncoso MF, Vanzulli SI, Rabinovich GA, Mariño KV, Elola MT. Ferragut F, et al. Among authors: cagnoni aj. Biochim Biophys Acta Mol Cell Res. 2019 Aug;1866(8):1338-1352. doi: 10.1016/j.bbamcr.2019.03.010. Epub 2019 Mar 21. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30905597 Free article.
Crystal structures of peanut lectin in the presence of synthetic β-N- and β-S-galactosides disclose evidence for the recognition of different glycomimetic ligands.
Cagnoni AJ, Primo ED, Klinke S, Cano ME, Giordano W, Mariño KV, Kovensky J, Goldbaum FA, Uhrig ML, Otero LH. Cagnoni AJ, et al. Acta Crystallogr D Struct Biol. 2020 Nov 1;76(Pt 11):1080-1091. doi: 10.1107/S2059798320012371. Epub 2020 Oct 13. Acta Crystallogr D Struct Biol. 2020. PMID: 33135679
29 results