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A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation.
de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ Jr, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, Yang PL. de Wispelaere M, et al. Among authors: whelan spj. J Biol Chem. 2020 Feb 7;295(6):1694-1703. doi: 10.1074/jbc.RA119.011132. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914414 Free PMC article.
STING-dependent translation inhibition restricts RNA virus replication.
Franz KM, Neidermyer WJ, Tan YJ, Whelan SPJ, Kagan JC. Franz KM, et al. Among authors: whelan spj. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2058-E2067. doi: 10.1073/pnas.1716937115. Epub 2018 Feb 12. Proc Natl Acad Sci U S A. 2018. PMID: 29440426 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33485559
A broad-spectrum antiviral targeting entry of enveloped viruses.
Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. doi: 10.1073/pnas.0909587107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133606 Free PMC article.
173 results