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Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.
Chan YK, Wang SK, Chu CJ, Copland DA, Letizia AJ, Costa Verdera H, Chiang JJ, Sethi M, Wang MK, Neidermyer WJ Jr, Chan Y, Lim ET, Graveline AR, Sanchez M, Boyd RF, Vihtelic TS, Inciong RGCO, Slain JM, Alphonse PJ, Xue Y, Robinson-McCarthy LR, Tam JM, Jabbar MH, Sahu B, Adeniran JF, Muhuri M, Tai PWL, Xie J, Krause TB, Vernet A, Pezone M, Xiao R, Liu T, Wang W, Kaplan HJ, Gao G, Dick AD, Mingozzi F, McCall MA, Cepko CL, Church GM. Chan YK, et al. Among authors: neidermyer wj jr. Sci Transl Med. 2021 Feb 10;13(580):eabd3438. doi: 10.1126/scitranslmed.abd3438. Sci Transl Med. 2021. PMID: 33568518 Free PMC article.
A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation.
de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ Jr, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, Yang PL. de Wispelaere M, et al. Among authors: neidermyer wj jr. J Biol Chem. 2020 Feb 7;295(6):1694-1703. doi: 10.1074/jbc.RA119.011132. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914414 Free PMC article.
Polymorphisms in Rhesus Macaque Tetherin Are Associated with Differences in Acute Viremia in Simian Immunodeficiency Virus Δnef-Infected Animals.
Janaka SK, Tavakoli-Tameh A, Neidermyer WJ Jr, Serra-Moreno R, Hoxie JA, Desrosiers RC, Johnson RP, Lifson JD, Wolinsky SM, Evans DT. Janaka SK, et al. Among authors: neidermyer wj jr. J Virol. 2018 Oct 29;92(22):e00542-18. doi: 10.1128/JVI.00542-18. Print 2018 Nov 15. J Virol. 2018. PMID: 30135127 Free PMC article.
Tetherin upregulation in simian immunodeficiency virus-infected macaques.
Rahmberg AR, Neidermyer WJ Jr, Breed MW, Alvarez X, Midkiff CC, Piatak M Jr, Lifson JD, Evans DT. Rahmberg AR, et al. Among authors: neidermyer wj jr. J Virol. 2013 Dec;87(24):13917-21. doi: 10.1128/JVI.01757-13. Epub 2013 Oct 9. J Virol. 2013. PMID: 24109219 Free PMC article.