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Flavonoid-Derived Human Phenyl-γ-Valerolactone Metabolites Selectively Detoxify Amyloid-β Oligomers and Prevent Memory Impairment in a Mouse Model of Alzheimer's Disease.
Ruotolo R, Minato I, La Vitola P, Artioli L, Curti C, Franceschi V, Brindani N, Amidani D, Colombo L, Salmona M, Forloni G, Donofrio G, Balducci C, Del Rio D, Ottonello S. Ruotolo R, et al. Among authors: colombo l. Mol Nutr Food Res. 2020 Mar;64(5):e1900890. doi: 10.1002/mnfr.201900890. Epub 2020 Jan 16. Mol Nutr Food Res. 2020. PMID: 31914208
Toll-like receptor 4-dependent glial cell activation mediates the impairment in memory establishment induced by β-amyloid oligomers in an acute mouse model of Alzheimer's disease.
Balducci C, Frasca A, Zotti M, La Vitola P, Mhillaj E, Grigoli E, Iacobellis M, Grandi F, Messa M, Colombo L, Molteni M, Trabace L, Rossetti C, Salmona M, Forloni G. Balducci C, et al. Among authors: colombo l. Brain Behav Immun. 2017 Feb;60:188-197. doi: 10.1016/j.bbi.2016.10.012. Epub 2016 Oct 14. Brain Behav Immun. 2017. PMID: 27751869
Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein.
Balducci C, Beeg M, Stravalaci M, Bastone A, Sclip A, Biasini E, Tapella L, Colombo L, Manzoni C, Borsello T, Chiesa R, Gobbi M, Salmona M, Forloni G. Balducci C, et al. Among authors: colombo l. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2295-300. doi: 10.1073/pnas.0911829107. Epub 2010 Jan 19. Proc Natl Acad Sci U S A. 2010. PMID: 20133875 Free PMC article.
Multifunctional liposomes reduce brain β-amyloid burden and ameliorate memory impairment in Alzheimer's disease mouse models.
Balducci C, Mancini S, Minniti S, La Vitola P, Zotti M, Sancini G, Mauri M, Cagnotto A, Colombo L, Fiordaliso F, Grigoli E, Salmona M, Snellman A, Haaparanta-Solin M, Forloni G, Masserini M, Re F. Balducci C, et al. Among authors: colombo l. J Neurosci. 2014 Oct 15;34(42):14022-31. doi: 10.1523/JNEUROSCI.0284-14.2014. J Neurosci. 2014. PMID: 25319699 Free PMC article.
Anti-amyloidogenic activity of tetracyclines: studies in vitro.
Forloni G, Colombo L, Girola L, Tagliavini F, Salmona M. Forloni G, et al. Among authors: colombo l. FEBS Lett. 2001 Jan 5;487(3):404-7. doi: 10.1016/s0014-5793(00)02380-2. FEBS Lett. 2001. PMID: 11163366 Free article.
805 results