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Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.
Mooser C, Symeonidou IE, Leimbacher PA, Ribeiro A, Shorrocks AK, Jungmichel S, Larsen SC, Knechtle K, Jasrotia A, Zurbriggen D, Jeanrenaud A, Leikauf C, Fink D, Nielsen ML, Blackford AN, Stucki M. Mooser C, et al. Among authors: stucki m. Nat Commun. 2020 Jan 8;11(1):123. doi: 10.1038/s41467-019-13981-x. Nat Commun. 2020. PMID: 31913317 Free PMC article.
The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.
Larsen DH, Hari F, Clapperton JA, Gwerder M, Gutsche K, Altmeyer M, Jungmichel S, Toledo LI, Fink D, Rask MB, Grøfte M, Lukas C, Nielsen ML, Smerdon SJ, Lukas J, Stucki M. Larsen DH, et al. Among authors: stucki m. Nat Cell Biol. 2014 Aug;16(8):792-803. doi: 10.1038/ncb3007. Epub 2014 Jul 27. Nat Cell Biol. 2014. PMID: 25064736 Free PMC article.
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M. Leimbacher PA, et al. Among authors: stucki m. Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18. Mol Cell. 2019. PMID: 30898438 Free PMC article.
The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis.
De Marco Zompit M, Esteban MT, Mooser C, Adam S, Rossi SE, Jeanrenaud A, Leimbacher PA, Fink D, Shorrocks AK, Blackford AN, Durocher D, Stucki M. De Marco Zompit M, et al. Among authors: stucki m. Nat Commun. 2022 Jul 16;13(1):4143. doi: 10.1038/s41467-022-31865-5. Nat Commun. 2022. PMID: 35842428 Free PMC article.
How Cells Respond to DNA Breaks in Mitosis.
Blackford AN, Stucki M. Blackford AN, et al. Among authors: stucki m. Trends Biochem Sci. 2020 Apr;45(4):321-331. doi: 10.1016/j.tibs.2019.12.010. Epub 2020 Jan 27. Trends Biochem Sci. 2020. PMID: 32001093 Free article. Review.
MDC1: The art of keeping things in focus.
Jungmichel S, Stucki M. Jungmichel S, et al. Among authors: stucki m. Chromosoma. 2010 Aug;119(4):337-49. doi: 10.1007/s00412-010-0266-9. Epub 2010 Mar 12. Chromosoma. 2010. PMID: 20224865 Free article. Review.
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Jungmichel S, Clapperton JA, Lloyd J, Hari FJ, Spycher C, Pavic L, Li J, Haire LF, Bonalli M, Larsen DH, Lukas C, Lukas J, MacMillan D, Nielsen ML, Stucki M, Smerdon SJ. Jungmichel S, et al. Among authors: stucki m. Nucleic Acids Res. 2012 May;40(9):3913-28. doi: 10.1093/nar/gkr1300. Epub 2012 Jan 10. Nucleic Acids Res. 2012. PMID: 22234878 Free PMC article.
Nucleolar responses to DNA double-strand breaks.
Larsen DH, Stucki M. Larsen DH, et al. Among authors: stucki m. Nucleic Acids Res. 2016 Jan 29;44(2):538-44. doi: 10.1093/nar/gkv1312. Epub 2015 Nov 28. Nucleic Acids Res. 2016. PMID: 26615196 Free PMC article. Review.
99 results