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Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.
Mooser C, Symeonidou IE, Leimbacher PA, Ribeiro A, Shorrocks AK, Jungmichel S, Larsen SC, Knechtle K, Jasrotia A, Zurbriggen D, Jeanrenaud A, Leikauf C, Fink D, Nielsen ML, Blackford AN, Stucki M. Mooser C, et al. Among authors: blackford an. Nat Commun. 2020 Jan 8;11(1):123. doi: 10.1038/s41467-019-13981-x. Nat Commun. 2020. PMID: 31913317 Free PMC article.
Structural Insight into BLM Recognition by TopBP1.
Sun L, Huang Y, Edwards RA, Yang S, Blackford AN, Niedzwiedz W, Glover JNM. Sun L, et al. Among authors: blackford an. Structure. 2017 Oct 3;25(10):1582-1588.e3. doi: 10.1016/j.str.2017.08.005. Epub 2017 Sep 14. Structure. 2017. PMID: 28919440 Free PMC article.
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M. Leimbacher PA, et al. Among authors: blackford an. Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18. Mol Cell. 2019. PMID: 30898438 Free PMC article.
How Cells Respond to DNA Breaks in Mitosis.
Blackford AN, Stucki M. Blackford AN, et al. Trends Biochem Sci. 2020 Apr;45(4):321-331. doi: 10.1016/j.tibs.2019.12.010. Epub 2020 Jan 27. Trends Biochem Sci. 2020. PMID: 32001093 Free article. Review.
35 results