Tyndale RF - Search Results

1

Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB.

Best LM, Williams B, Le Foll B, Mansouri E, Bazinet RP, Lin L, De Luca V, Lagzdins D, Rusjan P, Tyndale RF, Wilson AA, Hendershot CS, Heilig M, Houle S, Tong J, Kish SJ, Boileau I. Best LM, et al. Among authors: tyndale rf. Neuropsychopharmacology. 2020 Jul;45(8):1289-1296. doi: 10.1038/s41386-020-0606-2. Epub 2020 Jan 7. Neuropsychopharmacology. 2020. PMID: 31910433 Free PMC article.

2

Evidence of association between smoking and alpha7 nicotinic receptor subunit gene in schizophrenia patients.

De Luca V, Wong AH, Muller DJ, Wong GW, Tyndale RF, Kennedy JL. De Luca V, et al. Among authors: tyndale rf. Neuropsychopharmacology. 2004 Aug;29(8):1522-6. doi: 10.1038/sj.npp.1300466. Neuropsychopharmacology. 2004. PMID: 15100704

3

The fatty acid amide hydrolase C385A (P129T) missense variant in cannabis users: studies of drug use and dependence in Caucasians.

Tyndale RF, Payne JI, Gerber AL, Sipe JC. Tyndale RF, et al. Am J Med Genet B Neuropsychiatr Genet. 2007 Jul 5;144B(5):660-6. doi: 10.1002/ajmg.b.30491. Am J Med Genet B Neuropsychiatr Genet. 2007. PMID: 17290447

4

Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition.

Miksys S, Tyndale RF. Miksys S, et al. Among authors: tyndale rf. Neuropsychopharmacology. 2009 Feb;34(3):634-40. doi: 10.1038/npp.2008.110. Epub 2008 Jul 30. Neuropsychopharmacology. 2009. PMID: 18668033 Free PMC article.

5

Drug metabolism within the brain changes drug response: selective manipulation of brain CYP2B alters propofol effects.

Khokhar JY, Tyndale RF. Khokhar JY, et al. Among authors: tyndale rf. Neuropsychopharmacology. 2011 Feb;36(3):692-700. doi: 10.1038/npp.2010.202. Epub 2010 Nov 24. Neuropsychopharmacology. 2011. PMID: 21107310 Free PMC article.

6

The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients.

Mann A, Miksys SL, Gaedigk A, Kish SJ, Mash DC, Tyndale RF. Mann A, et al. Among authors: tyndale rf. Neurobiol Aging. 2012 Sep;33(9):2160-71. doi: 10.1016/j.neurobiolaging.2011.08.014. Epub 2011 Sep 29. Neurobiol Aging. 2012. PMID: 21958961

7

Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls.

Falcone M, Smith RM, Chenoweth MJ, Bhattacharjee AK, Kelsoe JR, Tyndale RF, Lerman C; Pharmacogenomics Research Network Central Nervous System Working Group. Falcone M, et al. Among authors: tyndale rf. Neuropsychopharmacology. 2013 Nov;38(12):2327-37. doi: 10.1038/npp.2013.152. Epub 2013 Jun 24. Neuropsychopharmacology. 2013. PMID: 23793356 Free PMC article. Review.

8

Nicotine Increases Codeine Analgesia Through the Induction of Brain CYP2D and Central Activation of Codeine to Morphine.

McMillan DM, Tyndale RF. McMillan DM, et al. Among authors: tyndale rf. Neuropsychopharmacology. 2015 Jun;40(7):1804-12. doi: 10.1038/npp.2015.32. Epub 2015 Jan 29. Neuropsychopharmacology. 2015. PMID: 25630571 Free PMC article.

9

Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration.

Garcia KL, Coen K, Miksys S, Lê AD, Tyndale RF. Garcia KL, et al. Among authors: tyndale rf. Neuropsychopharmacology. 2015 Jul;40(8):1910-8. doi: 10.1038/npp.2015.40. Epub 2015 Feb 5. Neuropsychopharmacology. 2015. PMID: 25652250 Free PMC article.

10

Cannabinoids: Friend or foe?

Le Foll B, Tyndale RF. Le Foll B, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2015 Jun;97(6):528-31. doi: 10.1002/cpt.119. Clin Pharmacol Ther. 2015. PMID: 25801347 Free PMC article.

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