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Targeting endothelial thioredoxin-interacting protein (TXNIP) protects from metabolic disorder-related impairment of vascular function and post-ischemic revascularisation.
Domingues A, Boisson-Vidal C, Marquet de Rouge P, Dizier B, Sadoine J, Mignon V, Vessières E, Henrion D, Escriou V, Bigey P, Chaussain C, Smadja DM, Nivet-Antoine V. Domingues A, et al. Among authors: smadja dm. Angiogenesis. 2020 May;23(2):249-264. doi: 10.1007/s10456-019-09704-x. Epub 2020 Jan 3. Angiogenesis. 2020. PMID: 31900750
The Wnt antagonist Dickkopf-1 increases endothelial progenitor cell angiogenic potential.
Smadja DM, d'Audigier C, Weiswald LB, Badoual C, Dangles-Marie V, Mauge L, Evrard S, Laurendeau I, Lallemand F, Germain S, Grelac F, Dizier B, Vidaud M, Bièche I, Gaussem P. Smadja DM, et al. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2544-52. doi: 10.1161/ATVBAHA.110.213751. Epub 2010 Sep 16. Arterioscler Thromb Vasc Biol. 2010. PMID: 20847303
Thrombospondin-1 is a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties.
Smadja DM, d'Audigier C, Bièche I, Evrard S, Mauge L, Dias JV, Labreuche J, Laurendeau I, Marsac B, Dizier B, Wagner-Ballon O, Boisson-Vidal C, Morandi V, Duong-Van-Huyen JP, Bruneval P, Dignat-George F, Emmerich J, Gaussem P. Smadja DM, et al. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):551-9. doi: 10.1161/ATVBAHA.110.220624. Epub 2010 Dec 9. Arterioscler Thromb Vasc Biol. 2011. PMID: 21148423 Clinical Trial.
Forearm ischemia decreases endothelial colony-forming cell angiogenic potential.
Mauge L, Sabatier F, Boutouyrie P, D'Audigier C, Peyrard S, Bozec E, Blanchard A, Azizi M, Dizier B, Dignat-George F, Gaussem P, Smadja DM. Mauge L, et al. Among authors: smadja dm. Cytotherapy. 2014 Feb;16(2):213-24. doi: 10.1016/j.jcyt.2013.09.007. Epub 2013 Nov 23. Cytotherapy. 2014. PMID: 24280239
Targeting VEGFR1 on endothelial progenitors modulates their differentiation potential.
d'Audigier C, Gautier B, Yon A, Alili JM, Guérin CL, Evrard SM, Godier A, Haviari S, Reille-Serroussi M, Huguenot F, Dizier B, Inguimbert N, Borgel D, Bièche I, Boisson-Vidal C, Roncal C, Carmeliet P, Vidal M, Gaussem P, Smadja DM. d'Audigier C, et al. Among authors: smadja dm. Angiogenesis. 2014 Jul;17(3):603-16. doi: 10.1007/s10456-013-9413-2. Epub 2014 Jan 14. Angiogenesis. 2014. PMID: 24419917
Thrombin receptor PAR-1 activation on endothelial progenitor cells enhances chemotaxis-associated genes expression and leukocyte recruitment by a COX-2-dependent mechanism.
d'Audigier C, Cochain C, Rossi E, Guérin CL, Bièche I, Blandinières A, Marsac B, Silvestre JS, Gaussem P, Smadja DM. d'Audigier C, et al. Among authors: smadja dm. Angiogenesis. 2015 Jul;18(3):347-59. doi: 10.1007/s10456-015-9471-8. Epub 2015 May 31. Angiogenesis. 2015. PMID: 26026674
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