Mella J - Search Results

1

Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays.

O Salas C, Zarate AM, Kryštof V, Mella J, Faundez M, Brea J, Loza MI, Brito I, Hendrychová D, Jorda R, Cabrera AR, Tapia RA, Espinosa-Bustos C. O Salas C, et al. Among authors: mella j. Int J Mol Sci. 2019 Dec 25;21(1):161. doi: 10.3390/ijms21010161. Int J Mol Sci. 2019. PMID: 31881717 Free PMC article.

2

Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.

Romero-Parra J, Chung H, Tapia RA, Faúndez M, Morales-Verdejo C, Lorca M, Lagos CF, Di Marzo V, David Pessoa-Mahana C, Mella J. Romero-Parra J, et al. Among authors: mella j. Eur J Pharm Sci. 2017 Apr 1;101:1-10. doi: 10.1016/j.ejps.2017.01.037. Epub 2017 Jan 28. Eur J Pharm Sci. 2017. PMID: 28137469

3

2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β₃-Adrenergic Activity.

Apablaza G, Montoya L, Morales-Verdejo C, Mellado M, Cuellar M, Lagos CF, Soto-Delgado J, Chung H, Pessoa-Mahana CD, Mella J. Apablaza G, et al. Among authors: mella j. Molecules. 2017 Mar 5;22(3):404. doi: 10.3390/molecules22030404. Molecules. 2017. PMID: 28273884 Free PMC article.

4

Insights into the Structural Requirements of Potent Brassinosteroids as Vegetable Growth Promoters Using Second-Internode Elongation as Biological Activity: CoMFA and CoMSIA Studies.

Ferrer-Pertuz K, Espinoza L, Mella J. Ferrer-Pertuz K, et al. Among authors: mella j. Int J Mol Sci. 2017 Dec 17;18(12):2734. doi: 10.3390/ijms18122734. Int J Mol Sci. 2017. PMID: 29258205 Free PMC article.

5

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections.

Campanini-Salinas J, Andrades-Lagos J, Gonzalez Rocha G, Choquesillo-Lazarte D, Bollo Dragnic S, Faúndez M, Alarcón P, Silva F, Vidal R, Salas-Huenuleo E, Kogan M, Mella J, Recabarren Gajardo G, Vásquez-Velásquez D. Campanini-Salinas J, et al. Among authors: mella j. Molecules. 2018 Jul 19;23(7):1776. doi: 10.3390/molecules23071776. Molecules. 2018. PMID: 30029513 Free PMC article.

6

Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs.

Suárez-Rozas C, Simpson S, Fuentes-Retamal S, Catalán M, Ferreira J, Theoduloz C, Mella J, Cabezas D, Cassels BK, Yáñez C, Castro-Castillo V. Suárez-Rozas C, et al. Among authors: mella j. Toxicol In Vitro. 2019 Feb;54:375-390. doi: 10.1016/j.tiv.2018.10.014. Epub 2018 Oct 30. Toxicol In Vitro. 2019. PMID: 30389605

7

State of the art of Smo antagonists for cancer therapy: advances in the target receptor and new ligand structures.

Espinosa-Bustos C, Mella J, Soto-Delgado J, Salas CO. Espinosa-Bustos C, et al. Among authors: mella j. Future Med Chem. 2019 Mar;11(6):617-638. doi: 10.4155/fmc-2018-0497. Epub 2019 Mar 26. Future Med Chem. 2019. PMID: 30912670 Review.

8

Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands.

Lorca M, Valdes Y, Chung H, Romero-Parra J, Pessoa-Mahana CD, Mella J. Lorca M, et al. Among authors: mella j. Int J Mol Sci. 2019 May 21;20(10):2510. doi: 10.3390/ijms20102510. Int J Mol Sci. 2019. PMID: 31117309 Free PMC article.

9

Design, synthesis, antifungal activity, and structure-activity relationship studies of chalcones and hybrid dihydrochromane-chalcones.

Mellado M, Espinoza L, Madrid A, Mella J, Chávez-Weisser E, Diaz K, Cuellar M. Mellado M, et al. Among authors: mella j. Mol Divers. 2020 Aug;24(3):603-615. doi: 10.1007/s11030-019-09967-y. Epub 2019 Jun 3. Mol Divers. 2020. PMID: 31161394

10

New 2,6,9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia.

Bertrand J, Dostálová H, Krystof V, Jorda R, Castro A, Mella J, Espinosa-Bustos C, María Zarate A, Salas CO. Bertrand J, et al. Among authors: mella j. Bioorg Chem. 2020 Jan;94:103361. doi: 10.1016/j.bioorg.2019.103361. Epub 2019 Oct 17. Bioorg Chem. 2020. PMID: 31699386

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