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How selective are clinical CDK4/6 inhibitors?
Hendrychová D, Jorda R, Kryštof V. Hendrychová D, et al. Med Res Rev. 2021 May;41(3):1578-1598. doi: 10.1002/med.21769. Epub 2020 Dec 10. Med Res Rev. 2021. PMID: 33300617 Review.
2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling.
Shaldam MA, Hendrychová D, El-Haggar R, Vojáčková V, Majrashi TA, Elkaeed EB, Masurier N, Kryštof V, Tawfik HO, Eldehna WM. Shaldam MA, et al. Among authors: hendrychova d. Eur J Med Chem. 2023 Oct 5;258:115610. doi: 10.1016/j.ejmech.2023.115610. Epub 2023 Jun 27. Eur J Med Chem. 2023. PMID: 37437350
Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair.
Parisis N, Dans PD, Jbara M, Singh B, Schausi-Tiffoche D, Molina-Serrano D, Brun-Heath I, Hendrychová D, Maity SK, Buitrago D, Lema R, Nait Achour T, Giunta S, Girardot M, Talarek N, Rofidal V, Danezi K, Coudreuse D, Prioleau MN, Feil R, Orozco M, Brik A, Wu PJ, Krasinska L, Fisher D. Parisis N, et al. Among authors: hendrychova d. Nat Commun. 2023 Aug 22;14(1):5104. doi: 10.1038/s41467-023-40843-4. Nat Commun. 2023. PMID: 37607906 Free PMC article.